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Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections
NCT03079713 · View on ClinicalTrials.gov ↗
Study Summary
Intravitreal injections are an efficient method of delivering therapeutic levels of medications to the posterior segment of the eye. Prior to receiving an injection, there are various methods to provide ocular anesthesia. Vibration may have an anti-nociceptive effect by directly decreasing the sensitivity of peripheral nociceptors or by reducing signal transmission from peripheral nociceptors to the brain with activation of vibratory sensation pathways. The purpose of this study is to evaluate the use of a handheld fingertip vibrator compared to topical eye drops for pain control while performing intravitreal eye injections. A secondary objective of the study is to measure corneal and conjunctiva sensitivity with and without activation of the vibrator to the lower lid using a Luneau Cochet-Bonnet aesthesiometer.
Conditions Studied
Interventions
- DEVICE Handheld vibrator triggered during intravitreal injection for wet ARMD
- DEVICE Normal eye esthesiometry with and without vibration
- DEVICE Handheld vibrator not triggered during intravitreal injection for wet ARMD
Study Locations (1)
Pennsylvania
- MidAtlantic Retina-Wills Eye Hospital — Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2017-04-12 |
| Est. Completion | 2019-03-20 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03079713
The ClinicalTrials.gov registry entry for NCT03079713 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Wills Eye, which has 12 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Pain Control During Intravitreal Injections appearing as the primary indexed condition, and to 3 interventions — of which Handheld vibrator triggered during intravitreal injection for wet ARMD is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03079713 reports 1 study location spanning 1 distinct geographic area — top geographies include Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03079713 about?
NCT03079713 is a clinical study titled "Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections". Intravitreal injections are an efficient method of delivering therapeutic levels of medications to the posterior segment of the eye. Prior to receiving an injection, there are various methods to provide ocular anesthesia. Vibration may have an anti-nociceptive effect by directly decreasing the sensi...
What is the current status of trial NCT03079713?
This trial is currently completed. It is a NA study. The enrollment target is 110 participants. The study started on 2017-04-12. Estimated completion is 2019-03-20.
What conditions does trial NCT03079713 study?
This clinical trial studies the following conditions: Pain Control During Intravitreal Injections. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03079713?
The interventions under investigation include: Handheld vibrator triggered during intravitreal injection for wet ARMD (DEVICE), Normal eye esthesiometry with and without vibration (DEVICE), Handheld vibrator not triggered during intravitreal injection for wet ARMD (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03079713?
This trial is sponsored by Wills Eye, which has 12 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03079713 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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