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Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.
NCT03078907 · View on ClinicalTrials.gov ↗
Study Summary
The primary objective of this study is to evaluate the effect of selexipag on the physical activity of patients with pulmonary arterial hypertension (PAH) in their daily life, by using a wearable wrist device (actigraph). The actigraph will collect data on daily life physical activity in the patient's real environment. In addition, the PAH symptoms and their impacts will be assessed by using an electronic patient reported outcome measure in the patient's real environment. Patients will be assigned randomly to either selexipag or placebo.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Selexipag
Study Locations (20)
Other
- Medizinische Universität Innsbruck (MUI), Abt. für Pneumologie, Haus 2 — Innsbruck
- Krankenhaus der Elisabethinen, Servicestelle Klinische Studien — Linz
- Hôpital Bicêtre, ervice de Pneumologie et Réanimation respiratoire — Le Kremlin-Bicêtre
- CHRU de Lille - Hôpital Albert Calmette, Service de cardiologie — Lille
- Hospital Larrey CHU de Toulouse — Toulouse
North Carolina
- UNC Pulmonary Speciality Clinic — Chapel Hill
- Duke University School of Medicine, Duke Pulmonary Vascular Disease center — Durham
Ohio
- University of Cincinnati, Heart, Lung and Vascular Institute — Cincinnati
- CCF- Akron General Medical Hospital — Cleveland
Texas
- Methodist Clinical Trials — San Antonio
- University of Texas Health Science Center (San Antonio) — San Antonio
California
- LA Biomedical Research Institute — Torrance
Georgia
- Northside Hospital — Atlanta
Kentucky
- Kentuckiana Pulmonary Research Center — Louisville
Massachusetts
- Tufts Medical Center, Pulmonary/Critical Care & Sleep — Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 108 participants |
| Start Date | 2017-11-08 |
| Est. Completion | 2020-02-10 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03078907
The ClinicalTrials.gov registry entry for NCT03078907 describes a study currently listed as completed. It is categorized as Phase 4, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Actelion, which has 14 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Pulmonary Arterial Hypertension appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT03078907 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Other, North Carolina, Ohio. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT03078907 about?
NCT03078907 is a clinical study titled "Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension.". The primary objective of this study is to evaluate the effect of selexipag on the physical activity of patients with pulmonary arterial hypertension (PAH) in their daily life, by using a wearable wrist device (actigraph). The actigraph will collect data on daily life physical activity in the patient...
What is the current status of trial NCT03078907?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 108 participants. The study started on 2017-11-08. Estimated completion is 2020-02-10.
What conditions does trial NCT03078907 study?
This clinical trial studies the following conditions: Pulmonary Arterial Hypertension. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT03078907?
The interventions under investigation include: Placebo (DRUG), Selexipag (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT03078907?
This trial is sponsored by Actelion, which has 14 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT03078907 being conducted?
This trial has 20 study locations across California, Georgia, Kentucky, Massachusetts, Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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