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NCT03072381 · ClinicalTrials.gov registry record · Phase 2
PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis
A Phase 2 study of Chronic Lateral Epicondylosis, sponsored by University of Wisconsin, Madison.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT03072381: Completed Phase 2 study of Chronic Lateral Epicondylosis, sponsored by University of Wisconsin, Madison.
NCT03072381 is a Phase 2 study of Chronic Lateral Epicondylosis that has completed, run by University of Wisconsin, Madison. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03072381, a Phase 2 study of Chronic Lateral Epicondylosis, has completed, sponsored by University of Wisconsin, Madison.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The proposed project will be the first to assess pain- and function-dependent, elbow-specific quality of life and in-vivo mechanical properties of common extensor tendons post-treatment with PRP in a Level 1, RCT with subject and assessor blinding. The valuable data gained will significantly add to the knowledge base of treatment effects of PRP for a chronic tendinopathy. Positive findings of PRP compared to control (corticosteroid injection) would suggest future larger scale studies to help establish an optimal protocol for the nonsurgical management of CLE. Correlating US and shear wave acoustoelastography imaging assessments with validated clinical outcomes will provide a powerful tool for future outcomes analyses using a non-invasive imaging modality to monitor tissue healing both morphologically as well as biomechanically, and may even be used to evaluate injury risk.
Primary Outcome
Patients receiving a single PRP PEAK injection for CLE will report improved Quick-DASH upper limb disability questionnaire from baseline to 52 week follow-up compared to control subjects (corticosteroid group)
Conditions Studied
Interventions
- BIOLOGICAL Platelet Rich Plasma - Group 1
- DRUG Corticosteroid Control - Group 2
Study Locations (1)
Wisconsin
- Wisconsin Institute of Medical Research (WIMR) - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2017-01 |
| Est. Completion | 2020-10-28 |
| Phase | Phase 2 |
What the finished NCT03072381 record still lists
NCT03072381 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Chronic Lateral Epicondylosis appearing as the primary indexed condition, and to 2 interventions - of which Platelet Rich Plasma - Group 1 is the first listed.
NCT03072381 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT03072381 about?
NCT03072381 is a clinical study titled "PEAK Platelet Rich Plasma Injection Treatment for Chronic Lateral Epicondylosis". The proposed project will be the first to assess pain- and function-dependent, elbow-specific quality of life and in-vivo mechanical properties of common extensor tendons post-treatment with PRP in a Level 1, RCT with subject and assessor blinding. The valuable data gained will significantly add to ...
What is the current status of trial NCT03072381?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2017-01. Estimated completion is 2020-10-28.
What conditions does trial NCT03072381 study?
This clinical trial studies the following conditions: Chronic Lateral Epicondylosis.
What interventions are being tested in trial NCT03072381?
The interventions under investigation include: Platelet Rich Plasma - Group 1 (BIOLOGICAL), Corticosteroid Control - Group 2 (DRUG).
Who is sponsoring clinical trial NCT03072381?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03072381 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03072381's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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