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NCT03026777 · ClinicalTrials.gov registry record · Phase 4
Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation
A Phase 4 study, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- Completed
- Registry status
- Phase 4
- Development phase
- 337
- Enrollment target
NCT03026777: Completed Phase 4 study, sponsored by Louisiana State University Health Sciences Center in New Orleans.
NCT03026777 is a Phase 4 study that has completed, run by Louisiana State University Health Sciences Center in New Orleans. The registered enrollment target is 337 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (35% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03026777, a Phase 4 study, has completed, sponsored by Louisiana State University Health Sciences Center in New Orleans.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 337 participants
- Enrollment target
Study Summary
Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death. The prevention of complications during urgent and emergent endotracheal intubation is a key focus for airway management research. Post-intubation hypotension (PIH), a common complication of endotracheal intubation in the critically ill, may be prevented by a bolus of intravenous fluid prior to the start of the procedure, but this approach has not been examined in a prospective trial. There are no randomized trials of intravenous fluid administration to prevent PIH in critically ill adults. The investigators propose a randomized trial of fluid loading to prevent PIH in critically ill adults.
Primary Outcome
a composite endpoint defined as one or more of the following: * Death within 1 hour of intubation * Cardiac arrest within 1 hour of intubation * New systolic blood pressure \< 65 mmHg between induction and 2 minutes after completion of intubation * New or increased vasopressor receipt between induction and 2 minutes after completion of intubation
Interventions
- DRUG intravenous crystalloid fluid, 500 mL
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 337 participants |
| Start Date | 2017-01 |
| Est. Completion | 2018-01 |
| Phase | Phase 4 |
What the finished NCT03026777 record still lists
NCT03026777 is an interventional study that assigns participants to a tested intervention. The registered 337 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (35% lower).
The record links to 0 conditions, and to 1 intervention - of which intravenous crystalloid fluid, 500 mL is the first listed.
NCT03026777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03026777 about?
NCT03026777 is a clinical study titled "Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation". Endotracheal intubation is common in the care of critically ill patients. Complications of airway management in this setting are frequently encountered and may be associated with an increased risk of death. The prevention of complications during urgent and emergent endotracheal intubation is a key f...
What is the current status of trial NCT03026777?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 337 participants. The study started on 2017-01. Estimated completion is 2018-01.
What interventions are being tested in trial NCT03026777?
The interventions under investigation include: intravenous crystalloid fluid, 500 mL (DRUG).
Who is sponsoring clinical trial NCT03026777?
This trial is sponsored by Louisiana State University Health Sciences Center in New Orleans, which has 45 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03026777's enrollment target sits among peer trials
337 250th of 2000 higher than 1,751 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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