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NCT03020524 · ClinicalTrials.gov registry record · Early Phase 1
Autologous CD4 T-Cells in HIV (C34-CXCR4)
A Early Phase 1 study, sponsored by University of Pennsylvania.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 9
- Enrollment target
NCT03020524: Completed Early Phase 1 study, sponsored by University of Pennsylvania.
NCT03020524 is a Early Phase 1 study that has completed, run by University of Pennsylvania. The registered enrollment target is 9 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03020524, a Early Phase 1 study, has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 9 participants
- Enrollment target
Study Summary
A single cohort, open-label pilot study of the safety and tolerability of a single infusion of autologous CD4+ T-cells genetically modified with an HR2, C34-peptide conjugated to the CXCR4 N-terminus using a lentiviral vector in HIV-infected subjects. This is a first in human study of C34-CXCR4 T cells
Primary Outcome
assessed by DAIDS AE grading table v2.0 November 2014
Interventions
- BIOLOGICAL Autologous CD4 T-Cells
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2017-01 |
| Est. Completion | 2020-03 |
| Phase | Early Phase 1 |
What the finished NCT03020524 record still lists
NCT03020524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Autologous CD4 T-Cells is the first listed.
NCT03020524 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03020524 about?
NCT03020524 is a clinical study titled "Autologous CD4 T-Cells in HIV (C34-CXCR4)". A single cohort, open-label pilot study of the safety and tolerability of a single infusion of autologous CD4+ T-cells genetically modified with an HR2, C34-peptide conjugated to the CXCR4 N-terminus using a lentiviral vector in HIV-infected subjects. This is a first in human study of C34-CXCR4 T ce...
What is the current status of trial NCT03020524?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 9 participants. The study started on 2017-01. Estimated completion is 2020-03.
What interventions are being tested in trial NCT03020524?
The interventions under investigation include: Autologous CD4 T-Cells (BIOLOGICAL).
Who is sponsoring clinical trial NCT03020524?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03020524's enrollment target sits among peer trials
9 1746th of 2000 higher than 219 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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