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NCT02974764 · ClinicalTrials.gov registry record
Changes in Biomarkers From Blood Over Time in Patients With Pancreatic Adenocarcinoma
A clinical trial, sponsored by Johns Hopkins University.
- Completed
- Registry status
- 200
- Enrollment target
NCT02974764: Completed study, sponsored by Johns Hopkins University.
NCT02974764 is a clinical trial that has completed, run by Johns Hopkins University. The registered enrollment target is 200 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02974764 has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- 200 participants
- Enrollment target
Study Summary
Pancreatic adenocarcinoma (PDAC) is the fourth leading cause of cancer mortality in the United States. The high mortality for these tumors is primarily attributed to the late stage in which most patients are diagnosed, leading to a dismal 5-year survival of 6% for all stages of PDAC. Surgical resection offers the best chance for survival, but most patients only present with symptoms after the tumor has metastasized, and as a result are not operative candidates. This creates a need to both identify patients at an earlier stage while their cancer is still resectable, and predict the aggressiveness of the disease in order to better target treatment. In addition, even patients who receive curative surgery are at a high risk of developing recurrence of disease. Thus, there is also a need to detect recurrence early so appropriate treatment can be provided. As several adjuvant chemotherapeutic regimens are now available, it will be important to identify as soon as possible that the cancer has become refractory to a given therapy. This will allow one to progress to second or third line therapy more quickly while the tumor burden is smaller. This purpose of this study is to identify biomarkers in the blood of patients with PDAC and determine how they can change over time in relation to treatment to assess for any correlation with patient outcomes, response to treatment, recurrence of disease and overall survival. This study will be limited to patients who present to the Johns Hopkins Hospital between January 1, 2015 and December 31, 2018 with PDAC. Blood will be drawn from all consenting patients at the time of initial diagnosis and after treatment. Patients will undergo treatment for their cancer based on personal preference, standard guidelines and discussion with medical, radiation, and surgical oncologists. Patients who undergo surgical resection will also have an additional blood sample collected after resection, and patients who undergo chemotherapy and/or radiation wi
Interventions
- OTHER No intervention/exposures
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2016-03 |
| Est. Completion | 2018-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02974764
The ClinicalTrials.gov registry entry for NCT02974764 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which No intervention/exposures is the first listed.
NCT02974764 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02974764 about?
NCT02974764 is a clinical study titled "Changes in Biomarkers From Blood Over Time in Patients With Pancreatic Adenocarcinoma". Pancreatic adenocarcinoma (PDAC) is the fourth leading cause of cancer mortality in the United States. The high mortality for these tumors is primarily attributed to the late stage in which most patients are diagnosed, leading to a dismal 5-year survival of 6% for all stages of PDAC. Surgical resect...
What is the current status of trial NCT02974764?
This trial is currently completed. The enrollment target is 200 participants. The study started on 2016-03. Estimated completion is 2018-12.
What interventions are being tested in trial NCT02974764?
The interventions under investigation include: No intervention/exposures (OTHER).
Who is sponsoring clinical trial NCT02974764?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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