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NCT02971228 · ClinicalTrials.gov registry record · Phase 2

Feasibility Trial Testing the Bionic Pancreas With ZP4207

A Phase 2 study, sponsored by Zealand Pharma.

Completed
Registry status
Phase 2
Development phase
13
Enrollment target

NCT02971228: Completed Phase 2 study, sponsored by Zealand Pharma.

NCT02971228 is a Phase 2 study that has completed, run by Zealand Pharma. The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02971228, a Phase 2 study, has completed, sponsored by Zealand Pharma.

COMPLETED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

The purpose of this study was to determine whether the Bionic Pancreas with ZP4207 (dasiglucagon\*) was feasible to improve glycemic control in adults with type 1 diabetes mellitus. \*dasiglucagon is the proposed International Nonproprietary Name (pINN) for ZP4207

Primary Outcome

Safety and tolerability of ZP4207 in the BP using either the iPhone or the iLet platform, as measured by adverse events (AEs), local tolerability of infusion site reactions, and clinical laboratory parameters. See adverse events section for results on AEs by system organ class and preferred term. Clinical laboratory parameters in terms of overall 'investigations' AEs and abnormal hematology parameters that did not resolve by the follow-up visit are presented below. LLN = lower limit of the norm

Interventions

  • DRUG Glucagon
  • DRUG Insulin Lispro
  • DRUG ZP4207 (dasiglucagon)
  • DEVICE iPhone-based bionic pancreas
  • DEVICE iLet-based bionic pancreas

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2016-11
Est. Completion 2017-06-07
Phase Phase 2
Zealand Pharma

18 total trials

What the finished NCT02971228 record still lists

NCT02971228 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 5 interventions - of which Glucagon is the first listed.

NCT02971228 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02971228 about?

NCT02971228 is a clinical study titled "Feasibility Trial Testing the Bionic Pancreas With ZP4207". The purpose of this study was to determine whether the Bionic Pancreas with ZP4207 (dasiglucagon\*) was feasible to improve glycemic control in adults with type 1 diabetes mellitus. \*dasiglucagon is the proposed International Nonproprietary Name (pINN) for ZP4207

What is the current status of trial NCT02971228?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2016-11. Estimated completion is 2017-06-07.

What interventions are being tested in trial NCT02971228?

The interventions under investigation include: Glucagon (DRUG), Insulin Lispro (DRUG), ZP4207 (dasiglucagon) (DRUG), iPhone-based bionic pancreas (DEVICE), iLet-based bionic pancreas (DEVICE).

Who is sponsoring clinical trial NCT02971228?

This trial is sponsored by Zealand Pharma, which has 18 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02971228's enrollment target sits among peer trials

13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02971228, the US trial registry maintained by the National Library of Medicine. NCT02971228 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.