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NCT02971098 · ClinicalTrials.gov registry record · NA
Mechanisms of Skeletal Muscle Insulin Resistance in Older Adults
A NA study of Reduced Physical Activity, sponsored by University of Utah.
- Completed
- Registry status
- NA
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT02971098 is a NA study of Reduced Physical Activity that has completed, run by University of Utah. The registered enrollment target is 9 participants. The trial reports 1 study location across 1 state.
The verdict
NCT02971098, a NA study of Reduced Physical Activity, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
The over-65 population is not only increasing at an alarming rate, but because six out of 10 will be managing more than one chronic condition by 2030, they will make up a much greater proportion of hospitalizations than ever before. Hospitalizations for disease, injury, and/or surgery in this group are likely to impair physical mobility and, therefore, the older adults capacity to be physically active both during hospitalization and beyond. The resulting sedentary lifestyle is likely to be accepted as the "new normal", ultimately increasing the risk of skeletal muscle and metabolic dysfunction (e.g. impaired glucose disposal, insulin resistance). These devastating outcomes are neither inevitable nor necessary if prevented with an appropriate mechanism-based intervention. A novel mechanism that may contribute to physical inactivity-induced insulin resistance is accumulation of inflammation and ceramide within skeletal muscle. Of interest, increased skeletal muscle inflammation and ceramide has been tied to various metabolic disturbances such as diabetes and insulin resistance. However, it is currently unknown if skeletal muscle inflammation and ceramide are a key mechanism associated with insulin resistance due to physical inactivity in older adults.
Conditions Studied
Interventions
- PROCEDURE Reduced activity
Study Locations (1)
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2016-09 |
| Est. Completion | 2019-12-17 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02971098
The ClinicalTrials.gov registry entry for NCT02971098 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Utah, which has 818 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Reduced Physical Activity appearing as the primary indexed condition, and to 1 intervention - of which Reduced activity is the first listed.
NCT02971098 reports 1 study location spanning 1 distinct geographic area - top geographies include Utah.
Frequently Asked Questions
What is clinical trial NCT02971098 about?
NCT02971098 is a clinical study titled "Mechanisms of Skeletal Muscle Insulin Resistance in Older Adults". The over-65 population is not only increasing at an alarming rate, but because six out of 10 will be managing more than one chronic condition by 2030, they will make up a much greater proportion of hospitalizations than ever before. Hospitalizations for disease, injury, and/or surgery in this group ...
What is the current status of trial NCT02971098?
This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2016-09. Estimated completion is 2019-12-17.
What conditions does trial NCT02971098 study?
This clinical trial studies the following conditions: Reduced Physical Activity.
What interventions are being tested in trial NCT02971098?
The interventions under investigation include: Reduced activity (PROCEDURE).
Who is sponsoring clinical trial NCT02971098?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02971098 being conducted?
This trial has 1 study location across Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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