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NCT02965053 · ClinicalTrials.gov registry record · Phase 1

A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis

A Phase 1 study, sponsored by Chugai Pharmaceutical.

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT02965053 is a Phase 1 study that has completed, run by Chugai Pharmaceutical. The registered enrollment target is 26 participants.

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The verdict

NCT02965053, a Phase 1 study, has completed, sponsored by Chugai Pharmaceutical.

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

This study is a randomized study designed as a 2x2 cross-over in two periods (Period 1 and Period 2) to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of EOS789 in patients with chronic kidney disease (CKD) and hyperphosphatemia receiving hemodialysis. Period 1 is double-blind and Period 2 is open-label. Period 1 and Period 2 are identical with regard to the design, inclusion/exclusion criteria, and assessments. EOS789 and its combination with sevelamer carbonate are tested in Period 1 and Period 2 respectively.

Interventions

  • DRUG Placebo
  • DRUG Renvela
  • DRUG EOS789

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2016-12
Est. Completion 2018-08
Phase Phase 1

Sponsor

Chugai Pharmaceutical

17 total trials

What the Registry Record Tells You About NCT02965053

The ClinicalTrials.gov registry entry for NCT02965053 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Chugai Pharmaceutical, which has 17 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02965053 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02965053 about?

NCT02965053 is a clinical study titled "A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis". This study is a randomized study designed as a 2x2 cross-over in two periods (Period 1 and Period 2) to assess the safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of EOS789 in patients with chronic kidney disease (CKD) and hyperphosphatemia receiving hemodialysis. Period 1 is doub...

What is the current status of trial NCT02965053?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2016-12. Estimated completion is 2018-08.

What interventions are being tested in trial NCT02965053?

The interventions under investigation include: Placebo (DRUG), Renvela (DRUG), EOS789 (DRUG).

Who is sponsoring clinical trial NCT02965053?

This trial is sponsored by Chugai Pharmaceutical, which has 17 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.