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NCT02947087 · ClinicalTrials.gov registry record · Phase 1
Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis
A Phase 1 study, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
NCT02947087: Completed Phase 1 study, sponsored by Medical University of South Carolina.
NCT02947087 is a Phase 1 study that has completed, run by Medical University of South Carolina. The registered enrollment target is 48 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02947087, a Phase 1 study, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
Study Summary
Primary objective: To describe and compare the safety and efficacy of treatment with AAT in chronic pancreatitis patients who undergo total pancreatectomy and islet autotransplantation (TP-IAT).
Primary Outcome
Islet graft function will be measured by 4 hour mixed meal tolerance test (MMTT) at 365 days post transplantation. Specific measurement is the C-peptide area under the curve (AUC)
Interventions
- DRUG Placebo
- DRUG Prolastin-C
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2017-01-11 |
| Est. Completion | 2022-11-13 |
| Phase | Phase 1 |
What the finished NCT02947087 record still lists
NCT02947087 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (20% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02947087 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02947087 about?
NCT02947087 is a clinical study titled "Alpha-1 Antitrypsin (AAT) Enhances Islet Autograft Survival in Patients With Chronic Pancreatitis". Primary objective: To describe and compare the safety and efficacy of treatment with AAT in chronic pancreatitis patients who undergo total pancreatectomy and islet autotransplantation (TP-IAT).
What is the current status of trial NCT02947087?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2017-01-11. Estimated completion is 2022-11-13.
What interventions are being tested in trial NCT02947087?
The interventions under investigation include: Placebo (DRUG), Prolastin-C (DRUG).
Who is sponsoring clinical trial NCT02947087?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02947087's enrollment target sits among peer trials
48 1025th of 2000 higher than 948 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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