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NCT02945579 · ClinicalTrials.gov registry record · NA
Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy
A NA study of Invasive Breast Carcinoma and HER2/Neu Negative, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 8
- Study locations
NCT02945579 is a NA study of Invasive Breast Carcinoma and HER2/Neu Negative that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 120 participants, below the 482-participant average among 45 other Invasive Breast Carcinoma trials with a reported enrollment target (75% lower). The trial reports 8 study locations across 8 states.
The verdict
NCT02945579, a NA study of Invasive Breast Carcinoma and HER2/Neu Negative, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 8
- Study locations
Study Summary
This clinical trial studies eliminating surgery and/or radiation therapy in treating breast cancer patients. In HER2 positive and triple negative breast cancers, after systemic therapy, when image-guided biopsy shows no residual cancer, patients then receive standard breast radiotherapy with no surgery. In ER positive/HER2 negative breast cancers, after endocrine therapy and ablative radiotherapy, when image-guided biopsy shows no residual cancer, patients then receive standard endocrine therapy with no surgery. For patients who have HER2 positive and triple negative breast cancers and standard surgery, after systemic therapy, breast radiotherapy is being eliminated when the pathology from surgery shows no residual cancer.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Laboratory Biomarker Analysis
- OTHER Questionnaire Administration
- RADIATION Undergo EBRT
- RADIATION Partial Breast Irradiation
Study Locations (8)
Arizona
- MD Anderson Cancer Center - Banner - Gilbert
Florida
- Baptist MD Anderson Cancer Center - Jacksonville
Hawaii
- Queen's Medical Center - Honolulu
Minnesota
- Mayo Clinic - Rochester
New Jersey
- Cooper Hospital Univ Med Ctr, MD Anderson at Cooper Voorhees - Voorhees Township
North Carolina
- Carolinas Medical Center/Levine Cancer Institute - Charlotte
Pennsylvania
- University of Pittsburgh Cancer Institute (UPCI) - Pittsburgh
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2017-01-20 |
| Est. Completion | 2028-01-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02945579
The ClinicalTrials.gov registry entry for NCT02945579 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 482-participant average among 45 other Invasive Breast Carcinoma trials with a reported enrollment target (75% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.
The record links to 10 conditions, with Invasive Breast Carcinoma appearing as the primary indexed condition, and to 5 interventions - of which Quality-of-Life Assessment is the first listed.
NCT02945579 reports 8 study locations spanning 8 distinct geographic areas - top geographies include Arizona, Florida, Hawaii.
Frequently Asked Questions
What is clinical trial NCT02945579 about?
NCT02945579 is a clinical study titled "Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy". This clinical trial studies eliminating surgery and/or radiation therapy in treating breast cancer patients. In HER2 positive and triple negative breast cancers, after systemic therapy, when image-guided biopsy shows no residual cancer, patients then receive standard breast radiotherapy with no surg...
What is the current status of trial NCT02945579?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2017-01-20. Estimated completion is 2028-01-31.
What conditions does trial NCT02945579 study?
This clinical trial studies the following conditions: Invasive Breast Carcinoma, HER2/Neu Negative, Estrogen Receptor Negative, Progesterone Receptor Negative, HER2-Positive Breast Carcinoma.
What interventions are being tested in trial NCT02945579?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Laboratory Biomarker Analysis (OTHER), Questionnaire Administration (OTHER), Undergo EBRT (RADIATION), Partial Breast Irradiation (RADIATION).
Who is sponsoring clinical trial NCT02945579?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02945579 being conducted?
This trial has 8 study locations across Arizona, Florida, Hawaii, Minnesota, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.