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NCT02938013 · ClinicalTrials.gov registry record · Phase 4

deLIVER: Direct Acting Antiviral Effects on the Liver

A Phase 4 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 4
Development phase
15
Enrollment target

NCT02938013: Completed Phase 4 study, sponsored by Johns Hopkins University.

NCT02938013 is a Phase 4 study that has completed, run by Johns Hopkins University. The registered enrollment target is 15 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT02938013, a Phase 4 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 4
Development phase
15 participants
Enrollment target

Study Summary

Open-label, partially-randomized plasma and liver sampling study to assess hepatitis C virus (HCV) kinetics during treatment with two (Sofosbuvir/Velpatasvir) or three (Sofosbuvir/Velpatasvir/Voxilaprevir) direct acting antivirals (DAAs)

Primary Outcome

Estimate the total number of HCV-infected Hepatocytes (virus burden) for each participant between pre-treatment liver biopsy and post treatment liver biopsy samples using HCV Quantitative real time PCR. Comparison of total number of HCV-infected Hepatocytes (virus burden) were reported between HCV mono infection and co infection groups.

Interventions

  • DRUG Sofosbuvir/Velpatasvir (SOF/VEL)
  • DRUG Sofosbuvir/Velpatasvir/Voxilaprevir [SOF/VEL/VOX]

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2017-01
Est. Completion 2020-09-30
Phase Phase 4
Johns Hopkins University

1,448 total trials

What the finished NCT02938013 record still lists

NCT02938013 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Sofosbuvir/Velpatasvir (SOF/VEL) is the first listed.

NCT02938013 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02938013 about?

NCT02938013 is a clinical study titled "deLIVER: Direct Acting Antiviral Effects on the Liver". Open-label, partially-randomized plasma and liver sampling study to assess hepatitis C virus (HCV) kinetics during treatment with two (Sofosbuvir/Velpatasvir) or three (Sofosbuvir/Velpatasvir/Voxilaprevir) direct acting antivirals (DAAs)

What is the current status of trial NCT02938013?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2017-01. Estimated completion is 2020-09-30.

What interventions are being tested in trial NCT02938013?

The interventions under investigation include: Sofosbuvir/Velpatasvir (SOF/VEL) (DRUG), Sofosbuvir/Velpatasvir/Voxilaprevir [SOF/VEL/VOX] (DRUG).

Who is sponsoring clinical trial NCT02938013?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02938013's enrollment target sits among peer trials

15 1880th of 2000 higher than 100 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02938013, the US trial registry maintained by the National Library of Medicine. NCT02938013 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.