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NCT02919774 · ClinicalTrials.gov registry record · Phase 1
Pomaglumetad Effects on Glutamate Biomarkers
A Phase 1 study, sponsored by New York State Psychiatric Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 95
- Enrollment target
NCT02919774: Completed Phase 1 study, sponsored by New York State Psychiatric Institute.
NCT02919774 is a Phase 1 study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 95 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02919774, a Phase 1 study, has completed, sponsored by New York State Psychiatric Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 95 participants
- Enrollment target
Study Summary
The study will evaluate the effects of the mGluR2/3 partial agonist LY2140023 (Pomaglumetad Methionil, "POMA") at selected doses on ketamine-stimulated glutamate release in prefrontal cortex as measured by pharmacoBOLD fMRI (also termed resting BOLD fMRI).
Primary Outcome
pharmacoBOLD change, as summarized by the Amplitude measure
Interventions
- DRUG placebo
- DRUG POMA
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 95 participants |
| Start Date | 2016-10 |
| Est. Completion | 2018-05-25 |
| Phase | Phase 1 |
What the finished NCT02919774 record still lists
NCT02919774 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (58% higher).
The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.
NCT02919774 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02919774 about?
NCT02919774 is a clinical study titled "Pomaglumetad Effects on Glutamate Biomarkers". The study will evaluate the effects of the mGluR2/3 partial agonist LY2140023 (Pomaglumetad Methionil, "POMA") at selected doses on ketamine-stimulated glutamate release in prefrontal cortex as measured by pharmacoBOLD fMRI (also termed resting BOLD fMRI).
What is the current status of trial NCT02919774?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 95 participants. The study started on 2016-10. Estimated completion is 2018-05-25.
What interventions are being tested in trial NCT02919774?
The interventions under investigation include: placebo (DRUG), POMA (DRUG).
Who is sponsoring clinical trial NCT02919774?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02919774's enrollment target sits among peer trials
95 610th of 2000 higher than 1,386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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