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NCT02918617 · ClinicalTrials.gov registry record · Phase 2

Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream

A Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.

Completed
Registry status
Phase 2
Development phase
203
Enrollment target

NCT02918617: Completed Phase 2 study, sponsored by The University of Texas Health Science Center at San Antonio.

NCT02918617 is a Phase 2 study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 203 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02918617, a Phase 2 study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.

COMPLETED
Registry status
Phase 2
Development phase
203 participants
Enrollment target

Study Summary

This study will investigate the effectiveness of nanohydroxyapatite (nano-HAP)-containing toothpastes and cream to relieve dentin hypersensitivity, comparing it with those of a commercial desensitizing dentifrice containing calcium sodium phosphosilicate (Novamin® technology) and a standard fluoride dentifrice containing 1,500 ppm fluoride as sodium monofluorophosphate (MFP).

Primary Outcome

Patient's response to an air stimulus is recorded on a Visual Analog Scale of 0-100 with 0 representing no pain and 100 representing the worst possible pain.

Interventions

  • DRUG Control toothpaste containing Novamin® technology
  • DRUG Control toothpaste containing 1500 ppm fluoride as MFP
  • DRUG Test toothpaste with nano-HAP (high concentration)
  • DRUG Test toothpaste with nano-HAP (low concentration)
  • DRUG Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3

Trial Details

FieldValue
Enrollment Target 203 participants
Start Date 2015-05
Est. Completion 2016-09
Phase Phase 2

What the finished NCT02918617 record still lists

NCT02918617 is an interventional study that assigns participants to a tested intervention. The registered 203 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% higher).

The record links to 0 conditions, and to 5 interventions - of which Control toothpaste containing Novamin® technology is the first listed.

NCT02918617 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02918617 about?

NCT02918617 is a clinical study titled "Clinical Efficacy in Relieving Dentin Hypersensitivity of Nanohydroxyapatite-Containing Toothpastes and Cream". This study will investigate the effectiveness of nanohydroxyapatite (nano-HAP)-containing toothpastes and cream to relieve dentin hypersensitivity, comparing it with those of a commercial desensitizing dentifrice containing calcium sodium phosphosilicate (Novamin® technology) and a standard fluoride...

What is the current status of trial NCT02918617?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 203 participants. The study started on 2015-05. Estimated completion is 2016-09.

What interventions are being tested in trial NCT02918617?

The interventions under investigation include: Control toothpaste containing Novamin® technology (DRUG), Control toothpaste containing 1500 ppm fluoride as MFP (DRUG), Test toothpaste with nano-HAP (high concentration) (DRUG), Test toothpaste with nano-HAP (low concentration) (DRUG), Test toothpaste with nano-HAP and (Potassium Nitrate) KNO3 (DRUG).

Who is sponsoring clinical trial NCT02918617?

This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02918617's enrollment target sits among peer trials

203 301st of 2000 higher than 1,700 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02918617, the US trial registry maintained by the National Library of Medicine. NCT02918617 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.