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NCT02910973 · ClinicalTrials.gov registry record · NA
Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway
A NA study, sponsored by Northwell Health.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT02910973: Completed NA study, sponsored by Northwell Health.
NCT02910973 is a NA study that has completed, run by Northwell Health. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02910973, a NA study, has completed, sponsored by Northwell Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Persistent chronic inflammation is an important underlying event in multiple diseases including rheumatoid arthritis, inflammatory bowel diseases and type 2 diabetes. These disorders are characterized as inflammatory in part because of the important mediating role of pro-inflammatory cytokines in their pathogenesis. This study will investigate whether transcutaneous auricular electrical stimulation of the vagus nerve will affect and decrease the inflammatory cytokine response in healthy individuals.
Primary Outcome
Whole blood will be taken from patients and stimulated by lipopolysaccharide. Levels of TNF produced by the cells in the whole blood after 4 hours of incubation will be measured.
Interventions
- DEVICE Vagus Nerve Stimulation
- DEVICE Sham Vagus Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2016-09 |
| Est. Completion | 2023-12-13 |
| Phase | NA |
What the finished NCT02910973 record still lists
NCT02910973 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Vagus Nerve Stimulation is the first listed.
NCT02910973 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02910973 about?
NCT02910973 is a clinical study titled "Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway". Persistent chronic inflammation is an important underlying event in multiple diseases including rheumatoid arthritis, inflammatory bowel diseases and type 2 diabetes. These disorders are characterized as inflammatory in part because of the important mediating role of pro-inflammatory cytokines in th...
What is the current status of trial NCT02910973?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2016-09. Estimated completion is 2023-12-13.
What interventions are being tested in trial NCT02910973?
The interventions under investigation include: Vagus Nerve Stimulation (DEVICE), Sham Vagus Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT02910973?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02910973's enrollment target sits among peer trials
16 1871st of 2000 higher than 120 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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