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NCT02889016 · ClinicalTrials.gov registry record

Neurobiologic, Immunologic, and Rheumatologic Markers in Youth With PANS

A clinical trial of Pediatric Acute-Onset Neuropsychiatric Syndrome and PANS, sponsored by Stanford University.

Recruiting
Registry status
500
Enrollment target
1
Study location

NCT02889016: Recruiting study of Pediatric Acute-Onset Neuropsychiatric Syndrome and PANS, sponsored by Stanford University.

NCT02889016 is a study of Pediatric Acute-Onset Neuropsychiatric Syndrome and PANS that is actively recruiting participants, run by Stanford University. The registered enrollment target is 500 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02889016, a study of Pediatric Acute-Onset Neuropsychiatric Syndrome and PANS, is actively recruiting participants, sponsored by Stanford University.

RECRUITING
Registry status
500 participants
Enrollment target
1
Study location

Study Summary

This study is an investigation of the neurologic, immunologic, and rheumatologic markers of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). PANS is a condition characterized by the abrupt, dramatic onset of obsessive compulsive disorder (OCD) and/or eating restriction accompanied by equally abrupt and severe co-morbid neuropsychiatric symptoms, which include anxiety, emotional lability, depression, irritability, aggression, oppositionality, deterioration in school performance, behavioral (developmental) regression, sensory amplification, movement abnormalities, sleep disturbance, and urinary frequency. PANS is thought to be caused by infection, inflammation, or alternate triggers that is associated with a brain response that leads to these symptoms. The purpose of this study is to examine specific neurologic, immunologic, rheumatologic, and genomic, components in children with the acute-onset of psychiatric symptoms. This research may begin to uncover a much larger story of autoimmune processes that are involved in psychiatric disorders of childhood. By better understanding the etiologic components of psychiatric phenomenon, future treatments may be better targeted to underlying causes.

Primary Outcome

The investigators will report results of altered cerebral blood flow from patients with PANS.

Study Locations (1)

California

  • Stanford University - Palo Alto

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2013-03
Est. Completion 2028-03
Stanford University

1,744 total trials

What NCT02889016 shows while recruiting

NCT02889016 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap.

The record links to 4 conditions, with Pediatric Acute-Onset Neuropsychiatric Syndrome appearing as the primary indexed condition, and to 0 interventions.

NCT02889016 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT02889016 about?

NCT02889016 is a clinical study titled "Neurobiologic, Immunologic, and Rheumatologic Markers in Youth With PANS". This study is an investigation of the neurologic, immunologic, and rheumatologic markers of Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). PANS is a condition characterized by the abrupt, dramatic onset of obsessive compulsive disorder (OCD) and/or eating restriction accompanied by equally ...

What is the current status of trial NCT02889016?

This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2013-03. Estimated completion is 2028-03.

What conditions does trial NCT02889016 study?

This clinical trial studies the following conditions: Pediatric Acute-Onset Neuropsychiatric Syndrome, PANS, PANDAS, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections.

Who is sponsoring clinical trial NCT02889016?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02889016 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT02889016, the US trial registry maintained by the National Library of Medicine. NCT02889016 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.