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NCT02876159 · ClinicalTrials.gov registry record · Phase 4

The Immunologic Basis for an Attenuated Immune Response to the Influenza Vaccine After Repeated Annual Vaccination

A Phase 4 study, sponsored by Emory University.

Completed
Registry status
Phase 4
Development phase
20
Enrollment target

NCT02876159: Completed Phase 4 study, sponsored by Emory University.

NCT02876159 is a Phase 4 study that has completed, run by Emory University. The registered enrollment target is 20 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02876159, a Phase 4 study, has completed, sponsored by Emory University.

COMPLETED
Registry status
Phase 4
Development phase
20 participants
Enrollment target

Study Summary

This is a prospective pilot study designed to suggest differences in the immunologic response to the seasonal influenza vaccine in people with regular vaccination history compared to those vaccinated less regularly. Participants will receive one dose of the Food and Drug Administration (FDA) approved 2016-2017 seasonal influenza vaccine. Immune system data will be collected at standard time points. The duration of the study for each participant will be approximately 1 month.

Primary Outcome

Geometric mean serum HAI antibody titers serum HAI titer will be collected via blood draw. Titer for serum HAI antibodies will be calculated using the geometric mean. Change is defined as the difference in means from Day 1 to Day 29.

Interventions

  • BIOLOGICAL 2016-2017 Influenza Vaccine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2016-07
Est. Completion 2016-12-01
Phase Phase 4
Emory University

1,208 total trials

What the finished NCT02876159 record still lists

NCT02876159 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which 2016-2017 Influenza Vaccine is the first listed.

NCT02876159 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02876159 about?

NCT02876159 is a clinical study titled "The Immunologic Basis for an Attenuated Immune Response to the Influenza Vaccine After Repeated Annual Vaccination". This is a prospective pilot study designed to suggest differences in the immunologic response to the seasonal influenza vaccine in people with regular vaccination history compared to those vaccinated less regularly. Participants will receive one dose of the Food and Drug Administration (FDA) approve...

What is the current status of trial NCT02876159?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2016-07. Estimated completion is 2016-12-01.

What interventions are being tested in trial NCT02876159?

The interventions under investigation include: 2016-2017 Influenza Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT02876159?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02876159's enrollment target sits among peer trials

20 1753rd of 2000 higher than 167 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02876159, the US trial registry maintained by the National Library of Medicine. NCT02876159 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.