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NCT02871102 · ClinicalTrials.gov registry record · NA
Stress Index to Individualize Mechanical Ventilation in ARDS
A NA study, sponsored by Vanderbilt University.
- Terminated
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT02871102: Clinical Trial NA study, sponsored by Vanderbilt University.
NCT02871102 is a NA study that was terminated before completion, run by Vanderbilt University. The registered enrollment target is 4 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02871102, a NA study, was terminated before completion, sponsored by Vanderbilt University.
- TERMINATED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Acute respiratory distress syndrome (ARDS) is a widely prevalent and morbid disease for which the current standard treatment is supportive care and avoidance of complications with lung-protective ventilation. Lower-tidal volume ventilation has been largely accepted as a means of lung protective ventilation, but the mechanism for its effectiveness is not yet clear, and debate remains as to how best to choose positive end-expiratory pressure (PEEP). Reduction in driving pressure (plateau pressure minus PEEP) has been suggested as a possible means to minimize ventilator-induced lung injury. This protocol aims to identify the range of safe paired-settings of PEEP and tidal volume, with selection guided by driving pressure and the stress index, a tool to recognize potential lung hyperinflation during mechanical ventilation.
Primary Outcome
Mean absolute difference between tidal volume in cc/kg PBW prescribed by ARDSnet settings on ARDSnet PEEP versus maximal protective tidal volume defined by stress index \<1.05 at the ARDSnet PEEP on experimental protocol.
Interventions
- PROCEDURE Recruitment Maneuver with PEEP and Tidal Volume Optimization
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2016-08 |
| Est. Completion | 2017-12 |
| Phase | NA |
Why NCT02871102 stopped before completion
NCT02871102 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Recruitment Maneuver with PEEP and Tidal Volume Optimization is the first listed.
NCT02871102 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02871102 about?
NCT02871102 is a clinical study titled "Stress Index to Individualize Mechanical Ventilation in ARDS". Acute respiratory distress syndrome (ARDS) is a widely prevalent and morbid disease for which the current standard treatment is supportive care and avoidance of complications with lung-protective ventilation. Lower-tidal volume ventilation has been largely accepted as a means of lung protective vent...
What is the current status of trial NCT02871102?
This trial is currently terminated. It is a NA study. The enrollment target is 4 participants. The study started on 2016-08. Estimated completion is 2017-12.
What interventions are being tested in trial NCT02871102?
The interventions under investigation include: Recruitment Maneuver with PEEP and Tidal Volume Optimization (PROCEDURE).
Who is sponsoring clinical trial NCT02871102?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02871102's enrollment target sits among peer trials
4 1996th of 2000 higher than 5 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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