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NCT02855359 · ClinicalTrials.gov registry record · Phase 2

Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma

A Phase 2 study, sponsored by Seagen.

Terminated
Registry status
Phase 2
Development phase
24
Enrollment target

NCT02855359: Clinical Trial Phase 2 study, sponsored by Seagen.

NCT02855359 is a Phase 2 study that was terminated before completion, run by Seagen. The registered enrollment target is 24 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02855359, a Phase 2 study, was terminated before completion, sponsored by Seagen.

TERMINATED
Registry status
Phase 2
Development phase
24 participants
Enrollment target

Study Summary

This is a Phase 2 study to evaluate the combination of denintuzumab mafodotin in combination with RCHOP or RCHP compared with RCHOP alone as front-line therapy in patients with diffuse large B-cell lymphoma or follicular lymphoma Grade 3b.

Primary Outcome

Study did not progress to Part B.

Interventions

  • DRUG cyclophosphamide
  • DRUG doxorubicin
  • DRUG rituximab
  • DRUG vincristine
  • DRUG denintuzumab mafodotin

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2016-08
Est. Completion 2018-05-15
Phase Phase 2
Seagen

84 total trials

Why NCT02855359 stopped before completion

NCT02855359 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (82% lower).

The record links to 0 conditions, and to 5 interventions - of which cyclophosphamide is the first listed.

NCT02855359 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02855359 about?

NCT02855359 is a clinical study titled "Denintuzumab Mafodotin (SGN-CD19A) Combined With RCHOP or RCHP Versus RCHOP Alone in Diffuse Large B-Cell Lymphoma or Follicular Lymphoma". This is a Phase 2 study to evaluate the combination of denintuzumab mafodotin in combination with RCHOP or RCHP compared with RCHOP alone as front-line therapy in patients with diffuse large B-cell lymphoma or follicular lymphoma Grade 3b.

What is the current status of trial NCT02855359?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2016-08. Estimated completion is 2018-05-15.

What interventions are being tested in trial NCT02855359?

The interventions under investigation include: cyclophosphamide (DRUG), doxorubicin (DRUG), rituximab (DRUG), vincristine (DRUG), denintuzumab mafodotin (DRUG).

Who is sponsoring clinical trial NCT02855359?

This trial is sponsored by Seagen, which has 84 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02855359's enrollment target sits among peer trials

24 1756th of 2000 higher than 217 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02855359, the US trial registry maintained by the National Library of Medicine. NCT02855359 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.