Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02853968 · ClinicalTrials.gov registry record
Unlock the Cell: Castleman's Disease Flow Cytometry Study
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 130
- Enrollment target
NCT02853968: Completed study, sponsored by University of Pennsylvania.
NCT02853968 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 130 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02853968 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 130 participants
- Enrollment target
Study Summary
Castleman disease, a rare lymphoproliferative disorder, is characterized by inflammatory cytokine production and multiple organ system dysfunction. In this study, we will investigate inflammatory markers, cells, and signaling pathways in prospectively collected blood samples and/or buccal swabs or saliva using biochemical and RT-PCR techniques, proteomics, genomics, immunohistochemistry, storage for future use, cell culture treated with external stimuli, flow cytometry, and other molecular tests
Primary Outcome
Peripheral blood will be collected to isolate peripheral blood mononuclear cells (PBMCs) used to look at inflammatory cell profiling via FACS. This will tell us what specific profiles are dysregulated.
Interventions
- PROCEDURE Blood draw/buccal swab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2016-02 |
| Est. Completion | 2019-03-30 |
What the finished NCT02853968 record still lists
NCT02853968 is an observational study that tracks outcomes without assigning an intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Blood draw/buccal swab is the first listed.
NCT02853968 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02853968 about?
NCT02853968 is a clinical study titled "Unlock the Cell: Castleman's Disease Flow Cytometry Study". Castleman disease, a rare lymphoproliferative disorder, is characterized by inflammatory cytokine production and multiple organ system dysfunction. In this study, we will investigate inflammatory markers, cells, and signaling pathways in prospectively collected blood samples and/or buccal swabs or s...
What is the current status of trial NCT02853968?
This trial is currently completed. The enrollment target is 130 participants. The study started on 2016-02. Estimated completion is 2019-03-30.
What interventions are being tested in trial NCT02853968?
The interventions under investigation include: Blood draw/buccal swab (PROCEDURE).
Who is sponsoring clinical trial NCT02853968?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492036 · 130 participants
Long-Term Follow-Up of Recipient of Gene Transfer Research
- NCT01631617 · 130 participants · Phase 2
Effects of Treatments on Atopic Dermatitis
- NCT02368041 · 130 participants
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
- NCT02604277 · 130 participants · NA
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia