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NCT02849678 · ClinicalTrials.gov registry record · NA

A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery

A NA study, sponsored by Jacques E. Chelly.

Completed
Registry status
NA
Development phase
68
Enrollment target

NCT02849678: Completed NA study, sponsored by Jacques E. Chelly.

NCT02849678 is a NA study that has completed, run by Jacques E. Chelly. The registered enrollment target is 68 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02849678, a NA study, has completed, sponsored by Jacques E. Chelly.

COMPLETED
Registry status
NA
Development phase
68 participants
Enrollment target

Study Summary

This research study is testing whether the local anesthetic lidocaine is as effective as ropivacaine for post-operative pain control in continuous thoracic paravertebral nerve blocks. Ropivacaine and Lidocaine are FDA-approved drugs that has been successfully used in this hospital for post-operative pain control for the past few years, thus has become the standard drugs used for this nerve block. Lidocaine has numerous potential advantages over ropivacaine, such as faster onset of action, better safety profile and greater anti-inflammatory action. Catheters placed near both sides of a patient's spine for postoperative pain control are called thoracic paravertebral nerve blocks and are a part of routine care. Through those catheters, a "numbing" medication, or local anesthetic, to block the transmission of pain from the surgical incision to the spinal cord, thus reducing pain. The research part of the study is whether subjects will receive either the local anesthetic lidocaine or ropivacaine. The goal of this study is to determine whether the lidocaine controls pain better and facilitates a faster recovery after abdominal surgery than ropivacaine. In this research study, the investigators will compare patient-reported pain scores, any additional pain medication requirements for adequate pain control, time it takes for bowel function to return to normal following surgery, as well as the incidence of any side effects, such as numbness and weakness, subjects may experience between those receiving lidocaine versus those receiving ropivacaine. The investigators will screen 100 patients and enroll 60 subjects into this study.

Primary Outcome

The primary outcome of the study is the NRS score for pain at rest at 24 hours. The NRS Pain Assessment requires patients to select a number between 0 - 10 where 0 is no pain and 10 is the worst imaginable pain. Patients pick one whole number on this scale to describe their pain.

Interventions

  • DRUG Lidocaine
  • DRUG Ropivacaine

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2008-01
Est. Completion 2016-05
Phase NA
Jacques E. Chelly

10 total trials

What the finished NCT02849678 record still lists

NCT02849678 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (95% lower).

The record links to 0 conditions, and to 2 interventions - of which Lidocaine is the first listed.

NCT02849678 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02849678 about?

NCT02849678 is a clinical study titled "A Pain Study Comparing Two Commonly Used Medications to Treat Pain After Bowel Surgery". This research study is testing whether the local anesthetic lidocaine is as effective as ropivacaine for post-operative pain control in continuous thoracic paravertebral nerve blocks. Ropivacaine and Lidocaine are FDA-approved drugs that has been successfully used in this hospital for post-operative...

What is the current status of trial NCT02849678?

This trial is currently completed. It is a NA study. The enrollment target is 68 participants. The study started on 2008-01. Estimated completion is 2016-05.

What interventions are being tested in trial NCT02849678?

The interventions under investigation include: Lidocaine (DRUG), Ropivacaine (DRUG).

Who is sponsoring clinical trial NCT02849678?

This trial is sponsored by Jacques E. Chelly, which has 10 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02849678's enrollment target sits among peer trials

68 1133rd of 2000 higher than 862 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02849678, the US trial registry maintained by the National Library of Medicine. NCT02849678 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.