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NCT02843373 · ClinicalTrials.gov registry record

Brain-Based Biomarkers in Response to TMS in MDD

A clinical trial, sponsored by Stanford University.

Completed
Registry status
54
Enrollment target

NCT02843373: Completed study, sponsored by Stanford University.

NCT02843373 is a clinical trial that has completed, run by Stanford University. The registered enrollment target is 54 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02843373 has completed, sponsored by Stanford University.

COMPLETED
Registry status
54 participants
Enrollment target

Study Summary

The overarching goal of this research program is to elucidate causal and directional neural network- level abnormalities in depression, and how they are modulated by an individually-tailored, circuit-directed intervention. By using concurrent TMS and EEG, the investigators can overcome a major limitation of EEG - the inability to demonstrate causality. Here, we plan to recruit patients with medication-resistant depression undergoing rTMS treatment. At multiple time points, we will perform TMS-EEG to investigate the excitability and connectivity profiles of brain networks and how they are modulated during treatment. This study aims to provide objective brain network measures that can predict and track clinical response to TMS treatment. Findings from this study will be utilized to develop a novel, personalized treatment protocol based on individual brain networks.

Primary Outcome

From pre- to post-treatment, improvement will be based on enhanced excitability and connectivity

Interventions

  • DEVICE TMS

Trial Details

FieldValue
Enrollment Target 54 participants
Start Date 2016-03
Est. Completion 2019-12
Stanford University

1,744 total trials

What the finished NCT02843373 record still lists

NCT02843373 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 54 participants, a relatively small participant target.

The record links to 0 conditions, and to 1 intervention - of which TMS is the first listed.

NCT02843373 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02843373 about?

NCT02843373 is a clinical study titled "Brain-Based Biomarkers in Response to TMS in MDD". The overarching goal of this research program is to elucidate causal and directional neural network- level abnormalities in depression, and how they are modulated by an individually-tailored, circuit-directed intervention. By using concurrent TMS and EEG, the investigators can overcome a major limit...

What is the current status of trial NCT02843373?

This trial is currently completed. The enrollment target is 54 participants. The study started on 2016-03. Estimated completion is 2019-12.

What interventions are being tested in trial NCT02843373?

The interventions under investigation include: TMS (DEVICE).

Who is sponsoring clinical trial NCT02843373?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT02843373, the US trial registry maintained by the National Library of Medicine. NCT02843373 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.