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NCT02831283 · ClinicalTrials.gov registry record · Phase 2
Imaging Inflammation in Alzheimer's Disease
A Phase 2 study, sponsored by Patrick Lao.
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT02831283: Completed Phase 2 study, sponsored by Patrick Lao.
NCT02831283 is a Phase 2 study that has completed, run by Patrick Lao. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02831283, a Phase 2 study, has completed, sponsored by Patrick Lao.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
This study is being done to learn about inflammation and amyloid in Alzheimer's disease. A type of brain scan called a PET scan is used measure 1) inflammation and 2) abnormal accumulation of a the amount of a certain protein fragment called beta-amyloid (plaques) in the brain. These are thought to be involved in Alzheimer's disease. The investigators will also perform brain MRI and do tests to measure the participants' memory and thinking.
Primary Outcome
In vivo quantification radioligand binding to TSPO expression on microglia in the brain, reported as standardized uptake value ratio (SUVR).
Interventions
- DRUG 18F-Florbetaben
- DRUG 11C-PBR28
- PROCEDURE Lumbar puncture (optional)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2016-06 |
| Est. Completion | 2022-12 |
| Phase | Phase 2 |
What the finished NCT02831283 record still lists
NCT02831283 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 3 interventions - of which 18F-Florbetaben is the first listed.
NCT02831283 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02831283 about?
NCT02831283 is a clinical study titled "Imaging Inflammation in Alzheimer's Disease". This study is being done to learn about inflammation and amyloid in Alzheimer's disease. A type of brain scan called a PET scan is used measure 1) inflammation and 2) abnormal accumulation of a the amount of a certain protein fragment called beta-amyloid (plaques) in the brain. These are thought to ...
What is the current status of trial NCT02831283?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2016-06. Estimated completion is 2022-12.
What interventions are being tested in trial NCT02831283?
The interventions under investigation include: 18F-Florbetaben (DRUG), 11C-PBR28 (DRUG), Lumbar puncture (optional) (PROCEDURE).
Who is sponsoring clinical trial NCT02831283?
This trial is sponsored by Patrick Lao, which has 3 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02831283's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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