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NCT02819297 · ClinicalTrials.gov registry record · Phase 3

BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults

A Phase 3 study, sponsored by Braintree Laboratories.

Completed
Registry status
Phase 3
Development phase
1,020
Enrollment target

NCT02819297: Completed Phase 3 study, sponsored by Braintree Laboratories.

NCT02819297 is a Phase 3 study that has completed, run by Braintree Laboratories. The registered enrollment target is 1,020 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (32% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02819297, a Phase 3 study, has completed, sponsored by Braintree Laboratories.

COMPLETED
Registry status
Phase 3
Development phase
1,020 participants
Enrollment target

Study Summary

The objective of this study is to evaluate a daily dose of BLI400 Laxative for safety and efficacy versus placebo in constipated adults.

Primary Outcome

The primary endpoint is the proportion of subjects who are weekly responders for at least 9 out of 12 weeks, with at least 3 of these weeks occurring in the last 4 weeks of treatment. A weekly responder is a subject who has ≥ 3 CSBMs and an increase from baseline of \> 1 CSBM in that week.

Interventions

  • DRUG BLI400 Laxative
  • DRUG BLI400 Placebo

Trial Details

FieldValue
Enrollment Target 1,020 participants
Start Date 2016-06
Est. Completion 2017-06
Phase Phase 3
Braintree Laboratories

49 total trials

What the finished NCT02819297 record still lists

NCT02819297 is an interventional study that assigns participants to a tested intervention. Its 1,020 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (32% higher).

The record links to 0 conditions, and to 2 interventions - of which BLI400 Laxative is the first listed.

NCT02819297 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02819297 about?

NCT02819297 is a clinical study titled "BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults". The objective of this study is to evaluate a daily dose of BLI400 Laxative for safety and efficacy versus placebo in constipated adults.

What is the current status of trial NCT02819297?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,020 participants. The study started on 2016-06. Estimated completion is 2017-06.

What interventions are being tested in trial NCT02819297?

The interventions under investigation include: BLI400 Laxative (DRUG), BLI400 Placebo (DRUG).

Who is sponsoring clinical trial NCT02819297?

This trial is sponsored by Braintree Laboratories, which has 49 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02819297's enrollment target sits among peer trials

1,020 291st of 2000 higher than 1,708 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02819297, the US trial registry maintained by the National Library of Medicine. NCT02819297 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.