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NCT02807051 · ClinicalTrials.gov registry record · Phase 1
To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects
A Phase 1 study, sponsored by CTI BioPharma.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT02807051: Completed Phase 1 study, sponsored by CTI BioPharma.
NCT02807051 is a Phase 1 study that has completed, run by CTI BioPharma. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02807051, a Phase 1 study, has completed, sponsored by CTI BioPharma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
This will be an open-label, single-center, crossover, one-way, drug-interaction study to evaluate the effect of 500 mg clarithromycin BID (dosed to steady state) on the PK of a single 400-mg dose of pacritinib in healthy male and female subjects.
Primary Outcome
To estimate ratios of geometric mean values and the corresponding 90% confidence intervals
Interventions
- DRUG Pacritinib
- DRUG Clarithromycin
- DRUG Pacritinib and Clarithromycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-09 |
| Est. Completion | 2014-10 |
| Phase | Phase 1 |
What the finished NCT02807051 record still lists
NCT02807051 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 3 interventions - of which Pacritinib is the first listed.
NCT02807051 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02807051 about?
NCT02807051 is a clinical study titled "To Evaluate the Effect of Clarithromycin on the Systemic Exposure of Pacritinib in Healthy Subjects". This will be an open-label, single-center, crossover, one-way, drug-interaction study to evaluate the effect of 500 mg clarithromycin BID (dosed to steady state) on the PK of a single 400-mg dose of pacritinib in healthy male and female subjects.
What is the current status of trial NCT02807051?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2014-09. Estimated completion is 2014-10.
What interventions are being tested in trial NCT02807051?
The interventions under investigation include: Pacritinib (DRUG), Clarithromycin (DRUG), Pacritinib and Clarithromycin (DRUG).
Who is sponsoring clinical trial NCT02807051?
This trial is sponsored by CTI BioPharma, which has 28 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02807051's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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