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NCT02806869 · ClinicalTrials.gov registry record · NA
Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment
A NA study, sponsored by University of Michigan.
- Completed
- Registry status
- NA
- Development phase
- 48
- Enrollment target
NCT02806869: Completed NA study, sponsored by University of Michigan.
NCT02806869 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 48 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02806869, a NA study, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
Study Summary
In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study was to evaluate the in vivo drug dissolution and systemic absorption of the BCS Class IIa drug ibuprofen under fed and fasted conditions by direct sampling of stomach and small intestinal luminal content. Expanding current knowledge of drug dissolution in vivo will help to establish physiologically relevant in vitro models predictive of drug dissolution.
Primary Outcome
The pH of duodenal fluid was measured at multiple timepoints over a 7 hour period. The reported value represents the mean and standard deviation of duodenal fluid pH.
Interventions
- DRUG Single dose of ibuprofen (800 mg tablet)
- DIETARY_SUPPLEMENT Pulmocare, two 8.0 oz (236.6 mL) cans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2015-01 |
| Est. Completion | 2017-07 |
| Phase | NA |
What the finished NCT02806869 record still lists
NCT02806869 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Single dose of ibuprofen (800 mg tablet) is the first listed.
NCT02806869 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02806869 about?
NCT02806869 is a clinical study titled "Modernization of in vivo-in Vitro Oral Bioperformance Prediction and Assessment". In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study was to evaluate the in vivo drug dissolution and systemic absorption of the BCS Class IIa drug ibuprofen under fed and fasted conditions by direct sampling of stomach and small intes...
What is the current status of trial NCT02806869?
This trial is currently completed. It is a NA study. The enrollment target is 48 participants. The study started on 2015-01. Estimated completion is 2017-07.
What interventions are being tested in trial NCT02806869?
The interventions under investigation include: Single dose of ibuprofen (800 mg tablet) (DRUG), Pulmocare, two 8.0 oz (236.6 mL) cans (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02806869?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02806869's enrollment target sits among peer trials
48 1381st of 2000 higher than 601 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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