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NCT02776111 · ClinicalTrials.gov registry record
Microfluidics and Transcriptomics in Post Solid Organ Transplant Patients
A clinical trial, sponsored by University of Florida.
- Terminated
- Registry status
- 7
- Enrollment target
NCT02776111: Clinical Trial study, sponsored by University of Florida.
NCT02776111 is a clinical trial that was terminated before completion, run by University of Florida. The registered enrollment target is 7 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02776111 was terminated before completion, sponsored by University of Florida.
- TERMINATED
- Registry status
- 7 participants
- Enrollment target
Study Summary
The field of genomics is an exciting new field being applied in medicine. Its use in treating some cancers, sepsis and burn patients has been very promising. As knowledge of genomics and application of microarrays expands, researchers are developing more intelligent ways to provide individualized care for patients. The plan of this research study is to apply the use of genomics as a tool for transplant in several capacities. This research study is designed to develop methods of isolating relevant cell types via microarray plates, then extracting mRNA samples of those cell types and capturing their genetic profile. This will be done with the blood of up to ten healthy donors. Once this ability has been demonstrated, the next step will be to use these testing in several capacities in transplant patients. The research study plan involves following the genetic profile of 26 kidney transplant patients. One group will be followed prospectively starting at baseline, and then at various set time points. A second group will be sampled with the occurrence of clinical events. These events include viral, bacterial, and fungal infection, WBC \< 2.5 or biopsy proven rejection episodes or normal graft function. Thus, the intention of the study is to demonstrate how immunosuppression alters the expression of this genetic expression of these T cells. In doing so, the study will provide a better understanding of the specific and true immunosuppressed state for any given patient.
Primary Outcome
Standard collected clinical information of patients will identify over, optimal and under immunosuppressive states (IS) in kidney transplant (txp) recipients. In txp care, the definition of IS is defined by the clinical picture of the patient. Patients who have infections are over immunosuppressed, patients who have rejection are under immunosuppressed. Patients with neither and good graft function with normal Cr \& good urine output have optimal IS. The investigators hope to identify a genomic
Interventions
- OTHER Blood Sample
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2016-07 |
| Est. Completion | 2019-06-26 |
Why NCT02776111 stopped before completion
NCT02776111 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 7 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Blood Sample is the first listed.
NCT02776111 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02776111 about?
NCT02776111 is a clinical study titled "Microfluidics and Transcriptomics in Post Solid Organ Transplant Patients". The field of genomics is an exciting new field being applied in medicine. Its use in treating some cancers, sepsis and burn patients has been very promising. As knowledge of genomics and application of microarrays expands, researchers are developing more intelligent ways to provide individualized ca...
What is the current status of trial NCT02776111?
This trial is currently terminated. The enrollment target is 7 participants. The study started on 2016-07. Estimated completion is 2019-06-26.
What interventions are being tested in trial NCT02776111?
The interventions under investigation include: Blood Sample (OTHER).
Who is sponsoring clinical trial NCT02776111?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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