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NCT02769000 · ClinicalTrials.gov registry record · NA

Low Dose RT to Reduce Cerebral Amyloidosis in Early Alzheimer's

A NA study, sponsored by Virginia Commonwealth University.

Terminated
Registry status
NA
Development phase
5
Enrollment target

NCT02769000 is a NA study that was terminated before completion, run by Virginia Commonwealth University. The registered enrollment target is 5 participants.

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The verdict

NCT02769000, a NA study, was terminated before completion, sponsored by Virginia Commonwealth University.

TERMINATED
Registry status
NA
Development phase
5 participants
Enrollment target

Study Summary

Evaluate safety and toxicity/adverse events associated with delivery of low dose whole brain irradiation in patients with early Alzheimer's dementia according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) criteria.. As a secondary goal it will establish whether or not the intervention with low dose whole brain irradiation stabilizes or decreases cerebral amyloid deposits and whether these correlate with the recognized progression of Alzheimer's dementia. The investigators will also collect information from the FDG and Amyvid® PET Scans to determine if there is any correlation between neurocognitive/quality of life scores and changes in amyloid plaque size, number and location.

Interventions

  • RADIATION 10 GY in 5 daily fractions
  • RADIATION 20 GY in 10 daily fractions

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2016-05
Est. Completion 2019-03-15
Phase NA

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT02769000

The ClinicalTrials.gov registry entry for NCT02769000 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which 10 GY in 5 daily fractions is the first listed.

NCT02769000 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02769000 about?

NCT02769000 is a clinical study titled "Low Dose RT to Reduce Cerebral Amyloidosis in Early Alzheimer's". Evaluate safety and toxicity/adverse events associated with delivery of low dose whole brain irradiation in patients with early Alzheimer's dementia according to the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Associatio...

What is the current status of trial NCT02769000?

This trial is currently terminated. It is a NA study. The enrollment target is 5 participants. The study started on 2016-05. Estimated completion is 2019-03-15.

What interventions are being tested in trial NCT02769000?

The interventions under investigation include: 10 GY in 5 daily fractions (RADIATION), 20 GY in 10 daily fractions (RADIATION).

Who is sponsoring clinical trial NCT02769000?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.