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NCT02758015 · ClinicalTrials.gov registry record · NA

Effect of Betaine and Food on Gastric pH

A NA study of Healthy, sponsored by University of California, San Francisco.

Completed
Registry status
NA
Development phase
9
Enrollment target
1
Study location

NCT02758015: Completed NA study of Healthy, sponsored by University of California, San Francisco.

NCT02758015 is a NA study of Healthy that has completed, run by University of California, San Francisco. The registered enrollment target is 9 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02758015, a NA study of Healthy, has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
NA
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

Food will decrease stomach acidity due to its buffering effect.This has implications when providing drugs that are dosed with food but require higher levels of stomach acid, such as some medications commonly used for HIV patients. This study will attempt to determine the dose of betaine hydrochloride (over the counter acid supplement) at which the effect of food on stomach acid could be countered. Additionally, this study will evaluate the ability of a natural supplement (betaine hydrochloride) to affect the gastric pH following a standardized meal in healthy volunteers. The investigators predict that 4500mg of betaine hydrochloride will have the greatest effect on gastric pH.

Primary Outcome

After Heidelberg capsule is placed and baseline gastric levels have been recorded using the Heidelberg Capsule (HC), which sends real-time signals to a computer system that visually plots intestinal pH on a minute-by-minute basis, a standardized meal is given. Gastric pH is measured for 15 minutes after the administration of the meal.

Conditions Studied

Healthy

Interventions

  • OTHER Standardized Meal
  • DIETARY_SUPPLEMENT Betaine Hydrochloride 1500mg
  • DIETARY_SUPPLEMENT Betaine Hydrochloride 3000mg
  • DIETARY_SUPPLEMENT Betaine Hydrochloride 4500mg

Study Locations (1)

California

  • Clinical Research Center, UCSF - San Francisco

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2016-06
Est. Completion 2018-03-26
Phase NA
University of California, San Francisco

1,713 total trials

What the finished NCT02758015 record still lists

NCT02758015 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which Standardized Meal is the first listed.

NCT02758015 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT02758015 about?

NCT02758015 is a clinical study titled "Effect of Betaine and Food on Gastric pH". Food will decrease stomach acidity due to its buffering effect.This has implications when providing drugs that are dosed with food but require higher levels of stomach acid, such as some medications commonly used for HIV patients. This study will attempt to determine the dose of betaine hydrochlorid...

What is the current status of trial NCT02758015?

This trial is currently completed. It is a NA study. The enrollment target is 9 participants. The study started on 2016-06. Estimated completion is 2018-03-26.

What conditions does trial NCT02758015 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT02758015?

The interventions under investigation include: Standardized Meal (OTHER), Betaine Hydrochloride 1500mg (DIETARY_SUPPLEMENT), Betaine Hydrochloride 3000mg (DIETARY_SUPPLEMENT), Betaine Hydrochloride 4500mg (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT02758015?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02758015 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02758015's enrollment target sits among peer trials

9 1057th of 1090 higher than 31 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02758015, the US trial registry maintained by the National Library of Medicine. NCT02758015 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.