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NCT02752724 · ClinicalTrials.gov registry record · NA

Ketamine Anesthesia for Improvement of Depression in ECT

A NA study, sponsored by VA Puget Sound Health Care System.

Completed
Registry status
NA
Development phase
52
Enrollment target

NCT02752724: Completed NA study, sponsored by VA Puget Sound Health Care System.

NCT02752724 is a NA study that has completed, run by VA Puget Sound Health Care System. The registered enrollment target is 52 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02752724, a NA study, has completed, sponsored by VA Puget Sound Health Care System.

COMPLETED
Registry status
NA
Development phase
52 participants
Enrollment target

Study Summary

The purpose of this prospective randomized clinical trial is to determine if patients receiving ketamine as a part of general anesthesia during electroconvulsive therapy (ECT) rather than standard of care will have improvement in symptoms of depression after a course of ECT treatments. The investigators hypothesize that utilization of ketamine for induction of general anesthesia during ECT treatments will improve symptoms of depression better than standard care. This study is ONLY open to patients eligible to receive healthcare services through the Department of Veterans Affairs at the VA Puget Sound, which means service in the active military, naval or air service or separation under any condition other than dishonorable. Qualifications for VA health care benefits can be found at va.gov.

Primary Outcome

Evaluate the efficacy and safety of repeat anesthetic ketamine dosing during a complete index course of ECT compared with methohexital using change in a validated depression scoring tool (Patient Health Questionnaire 9) administered 24 hours prior to starting an ECT index course treatment (baseline) with a PHQ9 score 72 hours after the last/final ECT session for approximately fifty patients. The PHQ9 Scoring ranges from 0 to 27 in order to monitor depression severity over time for newly diagnose

Interventions

  • DRUG Ketamine
  • DRUG Methohexital

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2016-03
Est. Completion 2018-04-30
Phase NA
VA Puget Sound Health Care System

16 total trials

What the finished NCT02752724 record still lists

NCT02752724 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Ketamine is the first listed.

NCT02752724 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02752724 about?

NCT02752724 is a clinical study titled "Ketamine Anesthesia for Improvement of Depression in ECT". The purpose of this prospective randomized clinical trial is to determine if patients receiving ketamine as a part of general anesthesia during electroconvulsive therapy (ECT) rather than standard of care will have improvement in symptoms of depression after a course of ECT treatments. The investiga...

What is the current status of trial NCT02752724?

This trial is currently completed. It is a NA study. The enrollment target is 52 participants. The study started on 2016-03. Estimated completion is 2018-04-30.

What interventions are being tested in trial NCT02752724?

The interventions under investigation include: Ketamine (DRUG), Methohexital (DRUG).

Who is sponsoring clinical trial NCT02752724?

This trial is sponsored by VA Puget Sound Health Care System, which has 16 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02752724's enrollment target sits among peer trials

52 1272nd of 2000 higher than 722 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02752724, the US trial registry maintained by the National Library of Medicine. NCT02752724 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.