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NCT02747394 · ClinicalTrials.gov registry record · NA

Cognitive Training for Fragile X Syndrome

A NA study, sponsored by University of California, Davis.

Completed
Registry status
NA
Development phase
106
Enrollment target

NCT02747394 is a NA study that has completed, run by University of California, Davis. The registered enrollment target is 106 participants.

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The verdict

NCT02747394, a NA study, has completed, sponsored by University of California, Davis.

COMPLETED
Registry status
NA
Development phase
106 participants
Enrollment target

Study Summary

Individuals with fragile X syndrome (FXS) demonstrate profound executive function deficits that interfere with learning, socialization and emotion regulation. Extensive research focused on the animal models of FXS show that targeted pharmacological agents can normalize synaptic connectivity and reverse cognitive and behavioral deficits. This translational work has led to multiple national and international controlled trials in humans with FXS now underway. However, in contrast to the heavy focus on medication treatments, there have been no controlled trials to empirically-validate cognitive or behavioral interventions for FXS. The proposed study, the first non-pharmacological controlled trial for FXS, will evaluate the efficacy of Cogmed, a cognitive training program proven to enhance working memory and executive/frontal function in a variety of clinical populations. Demonstration of effective Cogmed training for FXS would represent a major advance in the field, one that may also generalize to other forms of intellectual disability. Furthermore, it is critical to determine whether the targeted pharmacological treatments can accelerate learning and cognitive development. Thus, the validation of Cogmed for FXS will provide a paradigm for testing hypotheses focused on combined efficacy of medication and cognitive training.

Interventions

  • OTHER Working Memory Training

Trial Details

FieldValue
Enrollment Target 106 participants
Start Date 2013-01
Est. Completion 2018-10-18
Phase NA

Sponsor

University of California, Davis

657 total trials

What the Registry Record Tells You About NCT02747394

The ClinicalTrials.gov registry entry for NCT02747394 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 106 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, Davis, which has 657 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Working Memory Training is the first listed.

NCT02747394 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02747394 about?

NCT02747394 is a clinical study titled "Cognitive Training for Fragile X Syndrome". Individuals with fragile X syndrome (FXS) demonstrate profound executive function deficits that interfere with learning, socialization and emotion regulation. Extensive research focused on the animal models of FXS show that targeted pharmacological agents can normalize synaptic connectivity and reve...

What is the current status of trial NCT02747394?

This trial is currently completed. It is a NA study. The enrollment target is 106 participants. The study started on 2013-01. Estimated completion is 2018-10-18.

What interventions are being tested in trial NCT02747394?

The interventions under investigation include: Working Memory Training (OTHER).

Who is sponsoring clinical trial NCT02747394?

This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

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