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NCT02743286 · ClinicalTrials.gov registry record · NA
Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting
A NA study, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT02743286: Completed NA study, sponsored by University of California, San Diego.
NCT02743286 is a NA study that has completed, run by University of California, San Diego. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02743286, a NA study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Sedentary behavior, characterized by excess sitting time during waking hours, is detrimental to health and increases cardiometabolic disease risk, independent of moderate-to-vigorous physical activity. The mechanisms that mediate this are unknown and there are no evidence-based methods known for effectively intervening on sedentary behavior. The consequences of prolonged sitting time are of particular interest in older adults as sedentary behavior and cardiometabolic disease risk both increase with aging and moderate-to-vigorous physical activity may not be feasible. This pilot study will assess interventions for sedentary older adults designed to interrupt prolonged sitting time. Interrupting sitting time through sit-to-stand transitions, and standing and walking breaks increases muscle use and blood flow in the lower parts of the body. Thus, the investigators believe that frequent sit-to-stand interruptions of sitting time are the most efficacious sedentary behavior interventions, compared to simply reducing sitting time or less frequent walking breaks, for improving health outcomes and healthy aging. The investigators hypothesize that frequency of sit-to-stands during a 5-hour sitting period will result in health benefits that can be observed with a simple 2-minute standing interruption, and that this will be associated with improvements in metabolism and endothelial function. This pilot, 10-participant study will 1) generate preliminary data for a revised Program Project Grant application to the National Institute of Aging (NIA) that focuses on postmenopausal women, the fastest growing aged population with high life-time risk of cardiometabolic risk. This pilot study will inform sitting interruption modality design for two projects in the investigators' Program Project Grant application: "Project 1: Sedentary Behavior Interrupted: A randomized crossover treatment trial of acute effects on biomarkers of healthy aging in the laboratory (86 participants)" and "Proj
Primary Outcome
Change in endothelial function will be assessed by femoral flow-mediated dilation (FMD) and blood pressure measurements collected during the course of each study visit condition. Intervention-induced change will be compared to change observed during the control condition.
Interventions
- BEHAVIORAL Frequent sit-to-stands
- BEHAVIORAL Walking breaks
- BEHAVIORAL Stand more
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2016-04 |
| Est. Completion | 2016-07 |
| Phase | NA |
What the finished NCT02743286 record still lists
NCT02743286 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 3 interventions - of which Frequent sit-to-stands is the first listed.
NCT02743286 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02743286 about?
NCT02743286 is a clinical study titled "Sedentary Behavior Interrupted - A Pilot Study of Acute Interventions on Prolonged Sitting". Sedentary behavior, characterized by excess sitting time during waking hours, is detrimental to health and increases cardiometabolic disease risk, independent of moderate-to-vigorous physical activity. The mechanisms that mediate this are unknown and there are no evidence-based methods known for eff...
What is the current status of trial NCT02743286?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2016-04. Estimated completion is 2016-07.
What interventions are being tested in trial NCT02743286?
The interventions under investigation include: Frequent sit-to-stands (BEHAVIORAL), Walking breaks (BEHAVIORAL), Stand more (BEHAVIORAL).
Who is sponsoring clinical trial NCT02743286?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02743286's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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