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NCT02734953 · ClinicalTrials.gov registry record · Phase 2
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH
A Phase 2 study, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
- Completed
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT02734953: Completed Phase 2 study, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
NCT02734953 is a Phase 2 study that has completed, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). The registered enrollment target is 10 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02734953, a Phase 2 study, has completed, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
Pulmonary hypertension is characterized by an increase in the pressures in the blood supply to the lungs greater than a mean pressure of 25mmHg and a concomitant increase in overall pulmonary vascular resistance (PVR). In patients who have remodeling of their pulmonary vasculature, PVR will increase with exercise instead of decreasing as it would in normal patients. Based on published evidence, the investigators intend to investigate the effects of inhaled nitric oxide (iNO) on patients undergoing standard exercise techniques who have separately and previously had an implanted pulmonary artery monitoring device (CardioMems by St Jude Medical, Inc.) placed.
Primary Outcome
Difference between baseline (t=0) and post-intervention (t=2h)
Interventions
- DRUG Nitric Oxide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2016-04 |
| Est. Completion | 2016-12 |
| Phase | Phase 2 |
Sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)34 total trials
What the finished NCT02734953 record still lists
NCT02734953 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 1 intervention - of which Nitric Oxide is the first listed.
NCT02734953 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02734953 about?
NCT02734953 is a clinical study titled "Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH". Pulmonary hypertension is characterized by an increase in the pressures in the blood supply to the lungs greater than a mean pressure of 25mmHg and a concomitant increase in overall pulmonary vascular resistance (PVR). In patients who have remodeling of their pulmonary vasculature, PVR will increase...
What is the current status of trial NCT02734953?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2016-04. Estimated completion is 2016-12.
What interventions are being tested in trial NCT02734953?
The interventions under investigation include: Nitric Oxide (DRUG).
Who is sponsoring clinical trial NCT02734953?
This trial is sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), which has 34 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02734953's enrollment target sits among peer trials
10 1968th of 2000 higher than 12 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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