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NCT02734849 · ClinicalTrials.gov registry record · Phase 2
Study to Evaluate Multiple Doses in Patients With Nasal Polyposis
A Phase 2 study, sponsored by Allakos.
- Completed
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
NCT02734849: Completed Phase 2 study, sponsored by Allakos.
NCT02734849 is a Phase 2 study that has completed, run by Allakos. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02734849, a Phase 2 study, has completed, sponsored by Allakos.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
Study Summary
This is a phase 2 study to evaluate multiple doses of AK001 across 2 active doses. Pharmacodynamic activity will also be evaluated.
Primary Outcome
NPS was the sum of the right and left nostril scores, as evaluated by means of nasal endoscopy. Change in TPS from Baseline (prior to the first dose) to Week 12 (Day 84) was the primary outcome of the study. TPS ranges from 0 to 8 (scored 0 \[no polyp\] to 4 \[large polyps\] for each nostril), with a lower score indicating smaller-sized polyps, a higher scores mean a worse outcome.
Interventions
- DRUG Placebo
- DRUG AK001 low dose
- DRUG AK001 high dose
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2016-04 |
| Est. Completion | 2018-01 |
| Phase | Phase 2 |
What the finished NCT02734849 record still lists
NCT02734849 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT02734849 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02734849 about?
NCT02734849 is a clinical study titled "Study to Evaluate Multiple Doses in Patients With Nasal Polyposis". This is a phase 2 study to evaluate multiple doses of AK001 across 2 active doses. Pharmacodynamic activity will also be evaluated.
What is the current status of trial NCT02734849?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2016-04. Estimated completion is 2018-01.
What interventions are being tested in trial NCT02734849?
The interventions under investigation include: Placebo (DRUG), AK001 low dose (DRUG), AK001 high dose (DRUG).
Who is sponsoring clinical trial NCT02734849?
This trial is sponsored by Allakos, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02734849's enrollment target sits among peer trials
40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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