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NCT02725840 · ClinicalTrials.gov registry record
Breast Cancer Lung Late Effects
A clinical trial, sponsored by University of Florida.
- Completed
- Registry status
- 41
- Enrollment target
NCT02725840: Completed study, sponsored by University of Florida.
NCT02725840 is a clinical trial that has completed, run by University of Florida. The registered enrollment target is 41 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02725840 has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- 41 participants
- Enrollment target
Study Summary
Through improved early detection and treatment, the number of long term breast cancer survivors continues to increase. There are now 2.8 million breast cancer survivors in the U.S. Florida alone adds over 9,000 women to the survivorship pool each year. Most receive radiation treatment (RT) of the affected breast and chest wall to reduce risk of recurrence. Even with advanced radiation techniques for dose conformality to minimize exposure of the highly sensitive lung, 14% of breast cancer patients treated with radiation develop clinical pulmonary toxicity, with 4% overall experiencing high grade clinical toxicity. Early diagnosis and intervention to mitigate lung radiation toxicity is increasingly important for the long term care of these survivors. The investigators' goal is to better identify breast cancer patients at high risk for experiencing severe pulmonary toxicity requiring medical intervention, provide a means to identify toxicity early on, and tailor treatment and/or early intervention on a per-patient basis.
Primary Outcome
The investigators seek to identify differences between the treatment modalities (proton versus X-ray) in regards to the lower dose limits for change in number of small blood vessels as measured from chest CT scans and quantified using the team's analysis technique.
Interventions
- RADIATION Proton beam radiation therapy.
- RADIATION X-ray based radiation therapy
- PROCEDURE Computed Tomography (CT) Scan
- PROCEDURE Pulmonary Function Test (PFT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2016-05 |
| Est. Completion | 2022-01-14 |
What the finished NCT02725840 record still lists
NCT02725840 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 41 participants, a relatively small participant target.
The record links to 0 conditions, and to 4 interventions - of which Proton beam radiation therapy. is the first listed.
NCT02725840 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02725840 about?
NCT02725840 is a clinical study titled "Breast Cancer Lung Late Effects". Through improved early detection and treatment, the number of long term breast cancer survivors continues to increase. There are now 2.8 million breast cancer survivors in the U.S. Florida alone adds over 9,000 women to the survivorship pool each year. Most receive radiation treatment (RT) of the af...
What is the current status of trial NCT02725840?
This trial is currently completed. The enrollment target is 41 participants. The study started on 2016-05. Estimated completion is 2022-01-14.
What interventions are being tested in trial NCT02725840?
The interventions under investigation include: Proton beam radiation therapy. (RADIATION), X-ray based radiation therapy (RADIATION), Computed Tomography (CT) Scan (PROCEDURE), Pulmonary Function Test (PFT) (PROCEDURE).
Who is sponsoring clinical trial NCT02725840?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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