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NCT02725632 · ClinicalTrials.gov registry record · NA
Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)
A NA study, sponsored by Rhode Island Hospital.
- Completed
- Registry status
- NA
- Development phase
- 50
- Enrollment target
NCT02725632 is a NA study that has completed, run by Rhode Island Hospital. The registered enrollment target is 50 participants.
The verdict
NCT02725632, a NA study, has completed, sponsored by Rhode Island Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
Study Summary
This study is designed to test whether SCN5A mRNA processing is altered in OSA patients, which may contribute to their increased arrhythmic risk, and whether processing of SCN5A mRNA is modulated by CPAP treatment. Specific aims: 1. Compare sodium channel splicing variants in mild, moderate, or severe OSA patients at baseline to at 1 month after CPAP treatment. In addition, the baseline splicing variants of SCN5A in the OSA patients will be compared to an age-matched control group. 2. Hypoxia-associated upstream regulators of SCN5a mRNA splicing, Hypoxia-inducible factor 1-alpha (HIF-1α), RNA Binding Motif Protein 25 (RBM25) and LUC7-Like 3 Pre-MRNA Splicing Factor (LUC7L3), will be examined in OSA patients before and after 1 month of CPAP treatment.
Interventions
- DEVICE CPAP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2015-08 |
| Est. Completion | 2017-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02725632
The ClinicalTrials.gov registry entry for NCT02725632 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rhode Island Hospital, which has 130 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which CPAP is the first listed.
NCT02725632 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT02725632 about?
NCT02725632 is a clinical study titled "Sodium Channel Splicing in Obstructive Sleep Apnea (SOCS-OSA)". This study is designed to test whether SCN5A mRNA processing is altered in OSA patients, which may contribute to their increased arrhythmic risk, and whether processing of SCN5A mRNA is modulated by CPAP treatment. Specific aims: 1. Compare sodium channel splicing variants in mild, moderate, or se...
What is the current status of trial NCT02725632?
This trial is currently completed. It is a NA study. The enrollment target is 50 participants. The study started on 2015-08. Estimated completion is 2017-03.
What interventions are being tested in trial NCT02725632?
The interventions under investigation include: CPAP (DEVICE).
Who is sponsoring clinical trial NCT02725632?
This trial is sponsored by Rhode Island Hospital, which has 130 total clinical trials registered on ClinicalTrials.gov.
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