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NCT02714400 · ClinicalTrials.gov registry record · Phase 4

The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea

A Phase 4 study, sponsored by University of California, San Diego.

Completed
Registry status
Phase 4
Development phase
20
Enrollment target

NCT02714400 is a Phase 4 study that has completed, run by University of California, San Diego. The registered enrollment target is 20 participants.

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The verdict

NCT02714400, a Phase 4 study, has completed, sponsored by University of California, San Diego.

COMPLETED
Registry status
Phase 4
Development phase
20 participants
Enrollment target

Study Summary

The investigators hypothesis is that obstructive sleep apnea (OSA) patients with a low arousal threshold may wake up too early during a respiratory event, before upper airway muscles can be activated to achieve stable ventilation. Thus, strategies to manipulate the respiratory arousal threshold could potentially improve the quality of sleep and sleep disordered breathing. Agents that raise arousal threshold are therefore likely to benefit some patients with OSA. The overall goal of this project is to determine the importance of the arousal threshold in OSA, determine which patients might benefit from a raised arousal threshold, and test this hypothesis by using pharmacological manipulation of the arousal threshold to achieve this goal.

Interventions

  • DRUG Placebo
  • DRUG Venlafaxine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2016-03
Est. Completion 2016-07
Phase Phase 4

Sponsor

University of California, San Diego

775 total trials

What the Registry Record Tells You About NCT02714400

The ClinicalTrials.gov registry entry for NCT02714400 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02714400 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02714400 about?

NCT02714400 is a clinical study titled "The Impact of Venlafaxine on Apnea Hypopnea Index in Obstructive Sleep Apnea". The investigators hypothesis is that obstructive sleep apnea (OSA) patients with a low arousal threshold may wake up too early during a respiratory event, before upper airway muscles can be activated to achieve stable ventilation. Thus, strategies to manipulate the respiratory arousal threshold coul...

What is the current status of trial NCT02714400?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 20 participants. The study started on 2016-03. Estimated completion is 2016-07.

What interventions are being tested in trial NCT02714400?

The interventions under investigation include: Placebo (DRUG), Venlafaxine (DRUG).

Who is sponsoring clinical trial NCT02714400?

This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.