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COMPLETED Phase 2

Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection

NCT02713204 · View on ClinicalTrials.gov ↗

Study Summary

The primary objective of the study is to compare the efficacy of intravitreal (IVT)-administered REGN910-3 compared to intravitreal aflibercept injection (IAI).

Interventions

  • DRUG REGN910-3
  • DRUG Intravitreal Aflibercept Injection (IAI)

Study Locations (20)

California

  • Regeneron Investigational Site — Arcadia
  • Regeneron Investigational Site — Bakersfield
  • Regeneron Investigational Site — Beverly Hills
  • Regeneron Investigational Site — Encino
  • Regeneron Investigational Site 1 — Los Angeles
  • Regeneron Investigational Site 2 — Los Angeles
  • Regeneron Investigational Site — Mountain View
  • Regeneron Investigational Site — Oceanside
  • Regeneron Investigational Site 1 — Palm Desert
  • Regeneron Investigational Site 2 — Palm Desert
  • Regeneron Investigational Site — Palo Alto
  • Regeneron Investigational Site — Poway
  • Regeneron Investigational Site — Redlands
  • Regeneron Investigational Site — Sacramento

Arizona

  • Regeneron Investigational Site 1 — Phoenix
  • Regeneron Investigational Site 2 — Phoenix
  • Regeneron Investigational Site 3 — Phoenix
  • Regeneron Investigational Site 1 — Tucson
  • Regeneron Investigational Site 2 — Tucson

Alabama

  • Regeneron Investigational Site — Mobile

Trial Details

FieldValue
Enrollment Target 365 participants
Start Date 2016-03-31
Est. Completion 2017-10-03
Phase Phase 2

Sponsor

Regeneron Pharmaceuticals

290 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02713204

The ClinicalTrials.gov registry entry for NCT02713204 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 365 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Regeneron Pharmaceuticals, which has 290 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Neovascular Age-Related Macular Degeneration appearing as the primary indexed condition, and to 2 interventions — of which REGN910-3 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02713204 reports 20 study locations spanning 3 distinct geographic areas — top geographies include California, Arizona, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02713204 about?

NCT02713204 is a clinical study titled "Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection". The primary objective of the study is to compare the efficacy of intravitreal (IVT)-administered REGN910-3 compared to intravitreal aflibercept injection (IAI).

What is the current status of trial NCT02713204?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 365 participants. The study started on 2016-03-31. Estimated completion is 2017-10-03.

What conditions does trial NCT02713204 study?

This clinical trial studies the following conditions: Neovascular Age-Related Macular Degeneration. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02713204?

The interventions under investigation include: REGN910-3 (DRUG), Intravitreal Aflibercept Injection (IAI) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02713204?

This trial is sponsored by Regeneron Pharmaceuticals, which has 290 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02713204 being conducted?

This trial has 20 study locations across Alabama, Arizona, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial