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NCT02701985 · ClinicalTrials.gov registry record · Phase 2

A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome

A Phase 2 study of Sjogren's Syndrome, sponsored by Hoffmann-La Roche.

Completed
Registry status
Phase 2
Development phase
75
Enrollment target
20
Study locations

NCT02701985 is a Phase 2 study of Sjogren's Syndrome that has completed, run by Hoffmann-La Roche. The registered enrollment target is 75 participants, below the 285-participant average among 20 other Sjogren's Syndrome trials with a reported enrollment target (74% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT02701985, a Phase 2 study of Sjogren's Syndrome, has completed, sponsored by Hoffmann-La Roche.

COMPLETED
Registry status
Phase 2
Development phase
75 participants
Enrollment target
20
Study locations

Study Summary

This is a randomized, double-blind, placebo-controlled, two-treatment arm, parallel-group study designed to evaluate the effects of RO5459072 treatment on disease activity and symptoms of Sjogren's syndrome in adult participants with moderate to severe primary Sjogren's syndrome. The total duration of the study for each participant will be approximately 18 weeks (including screening).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG RO5459072

Study Locations (20)

Other

  • Hopital Avicenne, Paris - Bobigny
  • C.H.U. Ambroise Pare (AP-HP) - Boulogne-Billancourt
  • Hopital La Cavale Blanche; Rhumatologie - Brest
  • Hopital Lapeyronie; Immunologie Rhumatologie - Montpellier
  • Charité Research Organisation GmbH - Berlin
  • Szpital Uniwersytecki; nr 2 im. Dr J. Biziela; Klinika Reumatologii i Ukladowych Chorob - Bydgoszcz
  • MedPolonia - Poznan
  • Niepubliczny Opieki Zdrowotnej; Reumatika - Ctr Reum. - Warsaw

Pennsylvania

  • Altoona Center For Clinical Research - Duncansville
  • University of Pittsburgh Medical Center - Pittsburgh
  • Clinical Research Center of Reading - Wyomissing

California

  • Wallace Rheumatic Study Center - Beverly Hills

Colorado

  • Denver Arthritis Clinic - Denver

Louisiana

  • Ochsner Clinic Foundation - Baton Rouge

Maryland

  • John Hopkins Bayview Medical Center - Baltimore

Michigan

  • University Of Michigan - Ann Arbor

New York

  • Winthrop University Hospital - Mineola

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2016-07-05
Est. Completion 2017-07-10
Phase Phase 2

Sponsor

Hoffmann-La Roche

909 total trials

What the Registry Record Tells You About NCT02701985

The ClinicalTrials.gov registry entry for NCT02701985 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 75 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 285-participant average among 20 other Sjogren's Syndrome trials with a reported enrollment target (74% lower). The listed sponsor is Hoffmann-La Roche, which has 909 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Sjogren's Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02701985 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Other, Pennsylvania, California.

Frequently Asked Questions

What is clinical trial NCT02701985 about?

NCT02701985 is a clinical study titled "A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome". This is a randomized, double-blind, placebo-controlled, two-treatment arm, parallel-group study designed to evaluate the effects of RO5459072 treatment on disease activity and symptoms of Sjogren's syndrome in adult participants with moderate to severe primary Sjogren's syndrome. The total duration ...

What is the current status of trial NCT02701985?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2016-07-05. Estimated completion is 2017-07-10.

What conditions does trial NCT02701985 study?

This clinical trial studies the following conditions: Sjogren's Syndrome.

What interventions are being tested in trial NCT02701985?

The interventions under investigation include: Placebo (DRUG), RO5459072 (DRUG).

Who is sponsoring clinical trial NCT02701985?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02701985 being conducted?

This trial has 20 study locations across California, Colorado, Louisiana, Maryland, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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