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COMPLETED Phase 2

Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease

NCT02700919 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to compare the efficacy and safety of BCT197 when added on to standard of care in adult subjects with acute respiratory exacerbations of chronic obstructive pulmonary disease requiring hospitalization. Additionally, the study will characterize the pharmacokinetics of BCT197 in adults with COPD. The total duration of the study will be 26 weeks. Subjects will receive study treatment administration over a period of 5 days after randomization. It is expected that approximately 255 subjects will complete the study and follow-up.

Interventions

  • DRUG Placebo
  • DRUG BCT197

Study Locations (20)

Other

  • Mereo Research Site — Dupnitsa
  • Mereo Research Site — Gabrovo
  • Mereo Research Site — Kardzhali
  • Mereo Research Site — Kozloduy
  • Mereo Research Site — Kyustendil
  • Mereo Research Site — Lovech
  • Mereo Research Site — Montana
  • Mereo Research Site — Razgrad
  • Mereo Research Site — Rousse
  • Mereo Research Site — Shumen
  • Mereo Research Site — Sliven
  • Mereo Research Site — Sofia
  • Mereo Research Site — Kyjov
  • Mereo Research Site — Mělník
  • Mereo Research Site — Slaný
  • Mereo Research Site — Dresden
  • Mereo Research Site — Balassagyarmat

Indiana

  • Mereo Research Site — Michigan City

Maryland

  • Mereo Research Site — Baltimore

Wisconsin

  • Mereo Research Site — Milwaukee

Trial Details

FieldValue
Enrollment Target 282 participants
Start Date 2016-08-01
Est. Completion 2017-11-28
Phase Phase 2

Sponsor

Mereo BioPharma

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02700919

The ClinicalTrials.gov registry entry for NCT02700919 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 282 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mereo BioPharma, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Pulmonary Disease, Chronic Obstructive appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02700919 reports 20 study locations spanning 4 distinct geographic areas — top geographies include Other, Indiana, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02700919 about?

NCT02700919 is a clinical study titled "Efficacy and Safety of BCT197 in Subjects With Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease". The purpose of this study is to compare the efficacy and safety of BCT197 when added on to standard of care in adult subjects with acute respiratory exacerbations of chronic obstructive pulmonary disease requiring hospitalization. Additionally, the study will characterize the pharmacokinetics of BCT...

What is the current status of trial NCT02700919?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 282 participants. The study started on 2016-08-01. Estimated completion is 2017-11-28.

What conditions does trial NCT02700919 study?

This clinical trial studies the following conditions: Pulmonary Disease, Chronic Obstructive. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02700919?

The interventions under investigation include: Placebo (DRUG), BCT197 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02700919?

This trial is sponsored by Mereo BioPharma, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02700919 being conducted?

This trial has 20 study locations across Indiana, Maryland, Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial