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NCT02692391 · ClinicalTrials.gov registry record · Phase 3
A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis
A Phase 3 study, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 3
- Development phase
- 42
- Enrollment target
NCT02692391: Completed Phase 3 study, sponsored by University of Pittsburgh.
NCT02692391 is a Phase 3 study that has completed, run by University of Pittsburgh. The registered enrollment target is 42 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02692391, a Phase 3 study, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 42 participants
- Enrollment target
Study Summary
This is a randomized, double-blind, placebo-controlled pilot trial seeking to evaluate the efficacy of rectal indomethacin in abrogating systemic inflammation and subsequently organ failure and mortality in patients with AP and positive SIRS score.
Primary Outcome
SIRS is a simple clinical score, ranging from 0-4, that utilizes objective, routine clinical parameters (body temperature, heart rate, respiratory rate or arterial carbon dioxide tension and white blood count) that directly reflect the underlying inflammatory response. A lower change in SIRS score (negative number) indicates a better outcome (less inflammation).
Interventions
- DRUG Placebo
- DRUG Indomethacin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2013-07 |
| Est. Completion | 2019-12-30 |
| Phase | Phase 3 |
What the finished NCT02692391 record still lists
NCT02692391 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (95% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT02692391 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02692391 about?
NCT02692391 is a clinical study titled "A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis". This is a randomized, double-blind, placebo-controlled pilot trial seeking to evaluate the efficacy of rectal indomethacin in abrogating systemic inflammation and subsequently organ failure and mortality in patients with AP and positive SIRS score.
What is the current status of trial NCT02692391?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 42 participants. The study started on 2013-07. Estimated completion is 2019-12-30.
What interventions are being tested in trial NCT02692391?
The interventions under investigation include: Placebo (DRUG), Indomethacin (DRUG).
Who is sponsoring clinical trial NCT02692391?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT02692391's enrollment target sits among peer trials
42 1877th of 2000 higher than 124 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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