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NCT02678377 · ClinicalTrials.gov registry record · Phase 4
The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
A Phase 4 study of Stress Urinary Incontinence and Mixed Urinary Incontinence, sponsored by Northwestern University.
- Completed
- Registry status
- Phase 4
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT02678377: Completed Phase 4 study of Stress Urinary Incontinence and Mixed Urinary Incontinence, sponsored by Northwestern University.
NCT02678377 is a Phase 4 study of Stress Urinary Incontinence and Mixed Urinary Incontinence that has completed, run by Northwestern University. The registered enrollment target is 100 participants, below the 160-participant average among 35 other Stress Urinary Incontinence trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02678377, a Phase 4 study of Stress Urinary Incontinence and Mixed Urinary Incontinence, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
This double-blind randomized controlled trial seeks to find a better treatment for women with mixed urinary incontinence (both stress and urgency incontinence). The primary aim is to determine whether midurethral sling surgery combined with injections of onabotulinumtoxinA (Botox®) into the detrusor muscle of the bladder improves symptoms of mixed urinary incontinence better than sling surgery alone.
Primary Outcome
Mixed urinary incontinence symptoms will be assessed by the Patient Global Assessment of Improvement (PGI-I) survey, a patient oriented outcome
Conditions Studied
Interventions
- DRUG OnabotulinumtoxinA (Botox ®) Injections
- DRUG Saline Injections
Study Locations (1)
Illinois
- Northwestern Medicine Integrated Pelvic Health Clinic - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2016-02 |
| Est. Completion | 2021-07-26 |
| Phase | Phase 4 |
What the finished NCT02678377 record still lists
NCT02678377 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 160-participant average among 35 other Stress Urinary Incontinence trials with a reported enrollment target (37% lower).
The record links to 3 conditions, with Stress Urinary Incontinence appearing as the primary indexed condition, and to 2 interventions - of which OnabotulinumtoxinA (Botox ®) Injections is the first listed.
NCT02678377 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT02678377 about?
NCT02678377 is a clinical study titled "The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence". This double-blind randomized controlled trial seeks to find a better treatment for women with mixed urinary incontinence (both stress and urgency incontinence). The primary aim is to determine whether midurethral sling surgery combined with injections of onabotulinumtoxinA (Botox®) into the detrusor...
What is the current status of trial NCT02678377?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 100 participants. The study started on 2016-02. Estimated completion is 2021-07-26.
What conditions does trial NCT02678377 study?
This clinical trial studies the following conditions: Stress Urinary Incontinence, Mixed Urinary Incontinence, Urgency Incontinence.
What interventions are being tested in trial NCT02678377?
The interventions under investigation include: OnabotulinumtoxinA (Botox ®) Injections (DRUG), Saline Injections (DRUG).
Who is sponsoring clinical trial NCT02678377?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02678377 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stress Urinary Incontinence
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02678377's enrollment target sits among peer trials
100 15th of 35 higher than 20 of 35 other Stress Urinary Incontinence trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress Urinary Incontinence trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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