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NCT02676765 · ClinicalTrials.gov registry record · Phase 3

Desensitization and Cross-Desensitization During Oral Grass or Ragweed Pollen Immunotherapy

A Phase 3 study, sponsored by Virginia Commonwealth University.

Terminated
Registry status
Phase 3
Development phase
58
Enrollment target

NCT02676765: Clinical Trial Phase 3 study, sponsored by Virginia Commonwealth University.

NCT02676765 is a Phase 3 study that was terminated before completion, run by Virginia Commonwealth University. The registered enrollment target is 58 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02676765, a Phase 3 study, was terminated before completion, sponsored by Virginia Commonwealth University.

TERMINATED
Registry status
Phase 3
Development phase
58 participants
Enrollment target

Study Summary

The purpose of this study is to determine if sublingual allergen immunotherapy tablets work by inducing a state of desensitization in mast cells and basophils.

Primary Outcome

Change in the dose of allergen eliciting a wheal 3 mm greater than negative control upon skin prick testing (PC3)

Interventions

  • DRUG Placebo tablet
  • DRUG allergen extract tablet

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2016-06
Est. Completion 2018-01-18
Phase Phase 3
Virginia Commonwealth University

558 total trials

Why NCT02676765 stopped before completion

NCT02676765 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo tablet is the first listed.

NCT02676765 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02676765 about?

NCT02676765 is a clinical study titled "Desensitization and Cross-Desensitization During Oral Grass or Ragweed Pollen Immunotherapy". The purpose of this study is to determine if sublingual allergen immunotherapy tablets work by inducing a state of desensitization in mast cells and basophils.

What is the current status of trial NCT02676765?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 58 participants. The study started on 2016-06. Estimated completion is 2018-01-18.

What interventions are being tested in trial NCT02676765?

The interventions under investigation include: Placebo tablet (DRUG), allergen extract tablet (DRUG).

Who is sponsoring clinical trial NCT02676765?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02676765's enrollment target sits among peer trials

58 1825th of 2000 higher than 174 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02676765, the US trial registry maintained by the National Library of Medicine. NCT02676765 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.