Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02674321 · ClinicalTrials.gov registry record · Phase 1

A Pilot Study Of SD-809 (Deutetrabenazine) In Moderate To Severe Tourette Syndrome (TS)

A Phase 1 study, sponsored by Auspex Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
23
Enrollment target

NCT02674321: Completed Phase 1 study, sponsored by Auspex Pharmaceuticals.

NCT02674321 is a Phase 1 study that has completed, run by Auspex Pharmaceuticals. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02674321, a Phase 1 study, has completed, sponsored by Auspex Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
23 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate safety, tolerability and preliminary efficacy of SD-809 in the treatment of motor and phonic tics of Tourette Syndrome and to evaluate the pharmacokinetic of SD-809 and its metabolites.

Primary Outcome

Incidence of adverse events (AEs), serious AEs, severe AEs, drug related AEs, AEs leading to withdrawal.

Interventions

  • DRUG SD-809

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2014-07
Est. Completion 2015-06
Phase Phase 1
Auspex Pharmaceuticals

5 total trials

What the finished NCT02674321 record still lists

NCT02674321 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).

The record links to 0 conditions, and to 1 intervention - of which SD-809 is the first listed.

NCT02674321 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02674321 about?

NCT02674321 is a clinical study titled "A Pilot Study Of SD-809 (Deutetrabenazine) In Moderate To Severe Tourette Syndrome (TS)". The purpose of this study is to evaluate safety, tolerability and preliminary efficacy of SD-809 in the treatment of motor and phonic tics of Tourette Syndrome and to evaluate the pharmacokinetic of SD-809 and its metabolites.

What is the current status of trial NCT02674321?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2014-07. Estimated completion is 2015-06.

What interventions are being tested in trial NCT02674321?

The interventions under investigation include: SD-809 (DRUG).

Who is sponsoring clinical trial NCT02674321?

This trial is sponsored by Auspex Pharmaceuticals, which has 5 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02674321's enrollment target sits among peer trials

23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03616041 · 23 participants

    Capsule Endoscopy for Severe Hematochezia

  • NCT04348747 · 23 participants · Phase 2

    Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer

  • NCT04587687 · 23 participants · Phase 2

    Brentuximab Vedotin and Bendamustine for the Treatment of Relapsed or Refractory Follicular Lymphoma

  • NCT04715022 · 23 participants · Phase 1

    Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT02674321, the US trial registry maintained by the National Library of Medicine. NCT02674321 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.