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NCT02654704 · ClinicalTrials.gov registry record
Vaccination Responses in Young and Older Adults
A clinical trial, sponsored by Michigan State University.
- Terminated
- Registry status
- 61
- Enrollment target
NCT02654704: Clinical Trial study, sponsored by Michigan State University.
NCT02654704 is a clinical trial that was terminated before completion, run by Michigan State University. The registered enrollment target is 61 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02654704 was terminated before completion, sponsored by Michigan State University.
- TERMINATED
- Registry status
- 61 participants
- Enrollment target
Study Summary
To follow longitudinally healthy and immune-compromised responses to pneumococcal vaccination, in 60+ individuals towards the development of personalized medicine implementation (minimum enrollments in 2 age categories: young adults\[18-25\], older adults \[55+\], within each category: 10+ healthy, 10+ asthma, 10+ immune-compromised \[e.g. leukemia or autoimmune disorders\]). The approach will profile thousands of molecular components utilizing high-throughput technologies and integrate these data to obtain personalized immune response to vaccination. The study will provide insights into immune response mechanisms specific to asthmatics, immune compromised and healthy individuals, as well as in response to vaccination. Additionally the differences in dynamic response across the two age groups will be investigated.
Primary Outcome
The study will construct RNA-expression, protein profiles and small molecule profiles on immune cells as these change over time prior to and following immune activation by the vaccine. The collective temporal patterns will be used to classify immune response. The outcome measured is an updated integrative Personal Omics Profile as reported at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341616/ . This is observational in nature to assess personalized medicine methodology for following immune res
Interventions
- BIOLOGICAL Pneumococcal Vaccination
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 61 participants |
| Start Date | 2015-11 |
| Est. Completion | 2020-07 |
Why NCT02654704 stopped before completion
NCT02654704 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 61 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Pneumococcal Vaccination is the first listed.
NCT02654704 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT02654704 about?
NCT02654704 is a clinical study titled "Vaccination Responses in Young and Older Adults". To follow longitudinally healthy and immune-compromised responses to pneumococcal vaccination, in 60+ individuals towards the development of personalized medicine implementation (minimum enrollments in 2 age categories: young adults\[18-25\], older adults \[55+\], within each category: 10+ healthy, ...
What is the current status of trial NCT02654704?
This trial is currently terminated. The enrollment target is 61 participants. The study started on 2015-11. Estimated completion is 2020-07.
What interventions are being tested in trial NCT02654704?
The interventions under investigation include: Pneumococcal Vaccination (BIOLOGICAL).
Who is sponsoring clinical trial NCT02654704?
This trial is sponsored by Michigan State University, which has 120 total clinical trials registered on ClinicalTrials.gov.
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