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A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2
NCT02649556 · View on ClinicalTrials.gov ↗
Study Summary
The objective of the ZRHR-ERS-09-EXT-US study is to further assess the effect of the Tobacco Heating System 2.2 (THS 2.2), a candidate Modified Risk Tobacco Product, compared to conventional cigarettes (CC) on the components of the "smokers' health profile" for a prolonged period of 26 weeks, providing additional information to the results of the original study ZRHR-ERS-09-US of 26-week exposure (NCT02396381). In total, the ZRHR-ERS-09-EXT-US study will extend the exposure period to 52 weeks.
Conditions Studied
Interventions
- OTHER CC
- OTHER THS 2.2
Study Locations (19)
Florida
- Clinical Research West Florida — Clearwater
- Covance, Inc — Daytona Beach
- Compass Research — Orlando
- Clinical Research West Florida — Tampa
- Compass Research — The Villages
North Carolina
- PMG Research of Cary — Cary
- PMG Research of Charlotte — Charlotte
- PMG Research of Raleigh — Raleigh
- PMG Research of Wilmington — Wilmington
Texas
- Benchmark — Austin
- Benchmark — Fort Worth
- Benchmark — San Angelo
Tennessee
- PMG Research of Bristol — Bristol
- NOCCR — Knoxville
Arizona
- Celerion Arizona — Tempe
Kentucky
- Central Kentucky Research Associate — Lexington
Nebraska
- Celerion Lincoln — Lincoln
Ohio
- Midwest Clinical Research — Dayton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 672 participants |
| Start Date | 2015-09-30 |
| Est. Completion | 2017-12-20 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02649556
The ClinicalTrials.gov registry entry for NCT02649556 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 672 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Philip Morris Products S.A., which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Smoking appearing as the primary indexed condition, and to 2 interventions — of which CC is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02649556 reports 19 study locations spanning 9 distinct geographic areas — top geographies include Florida, North Carolina, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02649556 about?
NCT02649556 is a clinical study titled "A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2". The objective of the ZRHR-ERS-09-EXT-US study is to further assess the effect of the Tobacco Heating System 2.2 (THS 2.2), a candidate Modified Risk Tobacco Product, compared to conventional cigarettes (CC) on the components of the "smokers' health profile" for a prolonged period of 26 weeks, provid...
What is the current status of trial NCT02649556?
This trial is currently completed. It is a NA study. The enrollment target is 672 participants. The study started on 2015-09-30. Estimated completion is 2017-12-20.
What conditions does trial NCT02649556 study?
This clinical trial studies the following conditions: Smoking. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02649556?
The interventions under investigation include: CC (OTHER), THS 2.2 (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02649556?
This trial is sponsored by Philip Morris Products S.A., which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02649556 being conducted?
This trial has 19 study locations across Arizona, Florida, Kentucky, Nebraska, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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