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NCT02648724 · ClinicalTrials.gov registry record · Phase 1

Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies

A Phase 1 study, sponsored by Symphogen A/S.

Completed
Registry status
Phase 1
Development phase
57
Enrollment target

NCT02648724: Completed Phase 1 study, sponsored by Symphogen A/S.

NCT02648724 is a Phase 1 study that has completed, run by Symphogen A/S. The registered enrollment target is 57 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02648724, a Phase 1 study, has completed, sponsored by Symphogen A/S.

COMPLETED
Registry status
Phase 1
Development phase
57 participants
Enrollment target

Study Summary

This is the first study to test Sym015 in humans. The primary purpose of this study is to see if Sym015 is safe and effective for patients with advanced solid tumor malignancies without available therapeutic options.

Primary Outcome

The primary objective of Part 1 was to assess the safety and tolerability of Sym015 on a Q2W schedule. This was assessed by evaluating the occurrence of dose-limiting toxicities (DLTs) during Cycle 1 of Sym015 administration. Q2W = every second week.

Interventions

  • DRUG Sym015

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2016-03
Est. Completion 2020-12
Phase Phase 1
Symphogen A/S

12 total trials

What the finished NCT02648724 record still lists

NCT02648724 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 57 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which Sym015 is the first listed.

NCT02648724 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02648724 about?

NCT02648724 is a clinical study titled "Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies". This is the first study to test Sym015 in humans. The primary purpose of this study is to see if Sym015 is safe and effective for patients with advanced solid tumor malignancies without available therapeutic options.

What is the current status of trial NCT02648724?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 57 participants. The study started on 2016-03. Estimated completion is 2020-12.

What interventions are being tested in trial NCT02648724?

The interventions under investigation include: Sym015 (DRUG).

Who is sponsoring clinical trial NCT02648724?

This trial is sponsored by Symphogen A/S, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02648724's enrollment target sits among peer trials

57 901st of 2000 higher than 1,099 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02648724, the US trial registry maintained by the National Library of Medicine. NCT02648724 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.