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NCT02637895 · ClinicalTrials.gov registry record · Phase 4

Vortioxetine for Posttraumatic Stress Disorder

A Phase 4 study, sponsored by University of Miami.

Completed
Registry status
Phase 4
Development phase
41
Enrollment target

NCT02637895: Completed Phase 4 study, sponsored by University of Miami.

NCT02637895 is a Phase 4 study that has completed, run by University of Miami. The registered enrollment target is 41 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02637895, a Phase 4 study, has completed, sponsored by University of Miami.

COMPLETED
Registry status
Phase 4
Development phase
41 participants
Enrollment target

Study Summary

Post-traumatic stress disorder (PTSD) can result from having experienced or witnessed a traumatic event. Patients with PTSD symptoms can sometimes experience symptom relief after treatment with antidepressants; however, few patients experience complete symptom relief. There is a need to develop new treatments for PTSD. This study will evaluate if 12 weeks of using Vortioxetine relieves PTSD symptoms. Vortioxetine has been approved for the treatment of depression; however, Vortioxetine has not been approved by the Food and Drug Administration for the treatment of PTSD.

Primary Outcome

Clinician-Administered PTSD Scale (CAPS-5) has a total score ranging from 0-80 with the higher score indicating greater degree of PTSD symptom severity.

Interventions

  • DRUG Placebo
  • DRUG Vortioxetine

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2016-12
Est. Completion 2020-02-06
Phase Phase 4
University of Miami

721 total trials

What the finished NCT02637895 record still lists

NCT02637895 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02637895 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02637895 about?

NCT02637895 is a clinical study titled "Vortioxetine for Posttraumatic Stress Disorder". Post-traumatic stress disorder (PTSD) can result from having experienced or witnessed a traumatic event. Patients with PTSD symptoms can sometimes experience symptom relief after treatment with antidepressants; however, few patients experience complete symptom relief. There is a need to develop new ...

What is the current status of trial NCT02637895?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 41 participants. The study started on 2016-12. Estimated completion is 2020-02-06.

What interventions are being tested in trial NCT02637895?

The interventions under investigation include: Placebo (DRUG), Vortioxetine (DRUG).

Who is sponsoring clinical trial NCT02637895?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02637895's enrollment target sits among peer trials

41 1390th of 2000 higher than 604 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02637895, the US trial registry maintained by the National Library of Medicine. NCT02637895 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.