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NCT02621957 · ClinicalTrials.gov registry record · Phase 1

Effect of GDC-0810 on the Pharmacokinetics of Pravastatin in Healthy Female Subjects of Non-Childbearing Potential

A Phase 1 study of Breast Cancer, sponsored by Genentech.

Completed
Registry status
Phase 1
Development phase
15
Enrollment target
1
Study location

NCT02621957 is a Phase 1 study of Breast Cancer that has completed, run by Genentech. The registered enrollment target is 15 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02621957, a Phase 1 study of Breast Cancer, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 1
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

This study is to assess the pharmacokinetics (PK) of a single dose of pravastatin with and without concomitant GDC-0810 administration in healthy female subjects of non-childbearing potential. During Period 1 (Day -1 to Day 4) PK parameters of pravastatin will be determined in the absence of GDC-0810. During Period 2 (Days 5-28) PK parameters of pravastatin will be determined in the presence of GDC-0810.

Conditions Studied

Interventions

  • DRUG Pravastatin
  • DRUG GDC-0810

Study Locations (1)

Florida

  • - Daytona Beach

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2015-12
Est. Completion 2016-02
Phase Phase 1

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT02621957

The ClinicalTrials.gov registry entry for NCT02621957 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Pravastatin is the first listed.

NCT02621957 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT02621957 about?

NCT02621957 is a clinical study titled "Effect of GDC-0810 on the Pharmacokinetics of Pravastatin in Healthy Female Subjects of Non-Childbearing Potential". This study is to assess the pharmacokinetics (PK) of a single dose of pravastatin with and without concomitant GDC-0810 administration in healthy female subjects of non-childbearing potential. During Period 1 (Day -1 to Day 4) PK parameters of pravastatin will be determined in the absence of GDC-081...

What is the current status of trial NCT02621957?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2015-12. Estimated completion is 2016-02.

What conditions does trial NCT02621957 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT02621957?

The interventions under investigation include: Pravastatin (DRUG), GDC-0810 (DRUG).

Who is sponsoring clinical trial NCT02621957?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02621957 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.