Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in Human Immunodeficiency Virus-1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults

NCT02607930 · View on ClinicalTrials.gov ↗

Study Summary

The primary objective of this study is to evaluate the efficacy of a fixed dose combination (FDC) containing bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) versus a FDC containing abacavir/dolutegravir/lamivudine (ABC/DTG/3TC) in HIV-1 infected, antiretroviral treatment naive-adults.

Conditions Studied

Interventions

  • DRUG B/F/TAF
  • DRUG ABC/DTG/3TC
  • DRUG ABC/DTG/3TC Placebo
  • DRUG B/F/TAF Placebo

Study Locations (20)

California

  • Kaiser Permanente Medical Center — Los Angeles
  • Ruane Clinical Research Group, Inc. — Los Angeles
  • Anthony Martin Mills MD A Medical Corporation, DBA Mills Clinical Research — Los Angeles
  • Alameda Health System- Highland Hospital — Oakland
  • University of California Davis — Sacramento
  • Kaiser Permanente Medical Group — Sacramento
  • La Playa Medical Group — San Diego
  • Kaiser Permanente — San Francisco
  • Kaiser Permanente — San Leandro
  • The Lundquist Institute for BioMedical Innovation at Harbor-UCLA Medical Center — Torrance

District of Columbia

  • Whitman-Walker Institute — Washington D.C.
  • Providence Hospital - DC — Washington D.C.
  • Capital Medical Associates — Washington D.C.
  • Medical Faculty Associates — Washington D.C.

Arizona

  • Spectrum Medical Group — Phoenix
  • Pueblo Family Physicians — Phoenix

Florida

  • Therafirst Medical Center — Fort Lauderdale
  • Gary J. Richmond, M.D., P.A. — Fort Lauderdale

Alabama

  • University of Alabama at Birmingham — Birmingham

Colorado

  • Apex Research — Denver

Trial Details

FieldValue
Enrollment Target 631 participants
Start Date 2015-11-13
Est. Completion 2021-07-02
Phase Phase 3

Sponsor

Gilead Sciences

190 total trials

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02607930

The ClinicalTrials.gov registry entry for NCT02607930 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 631 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Gilead Sciences, which has 190 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with HIV-1 Infection appearing as the primary indexed condition, and to 4 interventions — of which B/F/TAF is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02607930 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, District of Columbia, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02607930 about?

NCT02607930 is a clinical study titled "Study to Evaluate the Safety and Efficacy of Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Abacavir/Dolutegravir/Lamivudine in Human Immunodeficiency Virus-1 (HIV-1) Infected, Antiretroviral Treatment-Naive Adults". The primary objective of this study is to evaluate the efficacy of a fixed dose combination (FDC) containing bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF) versus a FDC containing abacavir/dolutegravir/lamivudine (ABC/DTG/3TC) in HIV-1 infected, antiretroviral treatment naive-adults.

What is the current status of trial NCT02607930?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 631 participants. The study started on 2015-11-13. Estimated completion is 2021-07-02.

What conditions does trial NCT02607930 study?

This clinical trial studies the following conditions: HIV-1 Infection. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02607930?

The interventions under investigation include: B/F/TAF (DRUG), ABC/DTG/3TC (DRUG), ABC/DTG/3TC Placebo (DRUG), B/F/TAF Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02607930?

This trial is sponsored by Gilead Sciences, which has 190 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02607930 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial